Vitamin A supplementation for preventing morbidity and mortality in very low birthweight infants

Vitamin A is necessary for normal lung growth and the ongoing integrity of respiratory tract epithelial cells. Preterm infants have low vitamin A status at birth and this has been associated with increased risk of developing chronic lung disease. Several studies have been undertaken to assess whethe...

Full description

Saved in:
Bibliographic Details
Published in:Cochrane database of systematic reviews 2002 (4), p.CD000501-CD000501
Main Authors: Darlow, B A, Graham, P J
Format: Article
Language:English
Subjects:
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - prevention & control
Infant, Very Low Birth Weight
Lung Diseases - prevention & control
Randomized Controlled Trials as Topic
Vitamin A - therapeutic use
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Vitamin A is necessary for normal lung growth and the ongoing integrity of respiratory tract epithelial cells. Preterm infants have low vitamin A status at birth and this has been associated with increased risk of developing chronic lung disease. Several studies have been undertaken to assess whether vitamin A supplementation beyond that routinely given in multivitamin preparations can reduce the incidence of this outcome. To assess the benefit of supplementation with vitamin A in very low birthweight infants. Searches were made of the Oxford Database of Perinatal Trials, MEDLINE up to June 2002, Cochrane Controlled Trials Register (The Cochrane Library, Issue 2, 2002), and Science Citation Index. The reference lists of relevant trials, recent issues of paediatric and nutrition journals, abstracts and proceedings from relevant conferences in the English language were hand searched. Randomised controlled trials which compared the effects of supplemental vitamin A with standard vitamin A regimes in infants with birthweight
ISSN:1469-493X