Skin melanoma of the head and neck: Prognostic factors and recurrence‐free survival in 512 patients

The clinicopathologic and therapeutic data of 512 patients, with clinical Stage I invasive head and neck melanoma of the skin were retrospectively evaluated. There were 287 females and 225 males. Median age at primary‐surgery was 65 years (range, 18 to 96 years). Median observation period was 5 year...

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Bibliographic Details
Published in:Cancer 1992-03, Vol.69 (5), p.1153-1156
Main Authors: Andersson, Anders P., Gottlieb, Jorgen, Drzewiecki, Krzysztof T., Hou‐Jensen, Klaus, Sondergaard, Knud
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Head and Neck Neoplasms - mortality
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - surgery
Humans
Melanoma - mortality
Melanoma - pathology
Melanoma - surgery
Middle Aged
Neoplasm Invasiveness
Neoplasm Recurrence, Local - mortality
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Prognosis
Regression Analysis
Retrospective Studies
Risk Factors
Skin Neoplasms - mortality
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Survival Rate
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Summary:The clinicopathologic and therapeutic data of 512 patients, with clinical Stage I invasive head and neck melanoma of the skin were retrospectively evaluated. There were 287 females and 225 males. Median age at primary‐surgery was 65 years (range, 18 to 96 years). Median observation period was 5 years (range, 1 month to 25 years). Site of first recurrence was local in 7% (38 of 512), regional in 13% (67 of 512) and distant in 6% (31 of 512). Sex, age, ulcerated tumor, and tumor thickness were found to act as independent risk factors to recurrence‐free survival by Cox multivariate regression analysis. In addition, size of excision margin was found to be of no significance to survival without relapse when adjusting for the independent risk factors.
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.2820690515