Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn. (Palmae) husk fiber extract

The decoction of Cocos nucifera L. husk fiber has been used in northeastern Brazil traditional medicine for treatment of diarrhea and arthritis. Water extract obtained from coconut husk fiber and fractions from adsorption chromatography revealed antimicrobial activity against Staphylococcus aureus....

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Bibliographic Details
Published in:Research in microbiology 2002-12, Vol.153 (10), p.647-652
Main Authors: Esquenazi, Daniele, Wigg, Marcia D., Miranda, Mônica M.F.S., Rodrigues, Hugo M., Tostes, João B.F., Rozental, Sonia, da Silva, Antonio J.R., Alviano, Celuta S.
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents
Anti-Infective Agents - pharmacology
Antimicrobial activity
Antiviral activity
Antiviral Agents - pharmacology
Biological and medical sciences
Catechin - pharmacology
Catechins
Cercopithecus aethiops
Chromatography, High Pressure Liquid
Cocos - chemistry
Cocos nucifera
Condensed tannins
Flavonoids
General pharmacology
Herpesvirus 1, Human - drug effects
Humans
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenols - pharmacology
Plant Extracts - pharmacology
Polymers - pharmacology
Staphylococcus aureus - drug effects
Vero Cells
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Summary:The decoction of Cocos nucifera L. husk fiber has been used in northeastern Brazil traditional medicine for treatment of diarrhea and arthritis. Water extract obtained from coconut husk fiber and fractions from adsorption chromatography revealed antimicrobial activity against Staphylococcus aureus. The crude extract and one of the fractions rich in catechin also showed inhibitory activity against acyclovir-resistant herpes simplex virus type 1 (HSV-1-ACVr). All fractions were inactive against the fungi Candida albicans, Fonsecaea pedrosoi and Cryptococcus neoformans. Catechin and epicatechin together with condensed tannins (B-type procyanidins) were demonstrated to be the components of the water extract.
ISSN:0923-2508
1769-7123
DOI:10.1016/S0923-2508(02)01377-3