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Environmental regulation of mutation rates at specific sites

Recent studies on bacterial adaptation to stress suggest that bacteria can regulate the generation of mutations at specific sites in response to environmental conditions. Here, we review these findings and discuss the circumstances under which these mechanisms might prove advantageous. Recent studie...

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Published in:Trends in Microbiology 2002-12, Vol.10 (12), p.580-584
Main Authors: Massey, Ruth C, Buckling, Angus
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Language:English
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description Recent studies on bacterial adaptation to stress suggest that bacteria can regulate the generation of mutations at specific sites in response to environmental conditions. Here, we review these findings and discuss the circumstances under which these mechanisms might prove advantageous. Recent studies suggest that bacteria can egulate the generation of mutations at specific sites in response to environmental conditions. Here, we review these findings and discuss the circumstances under which these mechanisms might prove advantageous.
doi_str_mv 10.1016/S0966-842X(02)02475-7
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subjects adaptive change
Bacteria - genetics
contingency loci
Ecosystem
Environment
environmental stress
Genes, Bacterial
Mutation - genetics
mutation rates
Phenotype
phenotypic variation
selection
SOS response
Time Factors
type I fimbriae
title Environmental regulation of mutation rates at specific sites
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