Practical Aspects of Conducting Large-Scale Functional Magnetic Resonance Imaging Studies in Children

The potential benefits of functional magnetic resonance imaging (MRI) for the investigation of normal development have been limited by difficulties in its use with children. We describe the practical aspects, including failure rates, involved in conducting large-scale functional MRI studies with nor...

Full description

Saved in:
Bibliographic Details
Published in:Journal of child neurology 2002-12, Vol.17 (12), p.885-889
Main Authors: Byars, Anna Weber, Holland, Scott K., Strawsburg, Richard H., Bommer, Wendy, Dunn, R. Scott, Schmithorst, Vince J., Plante, Elena
Format: Article
Language:English
Subjects:
Adolescent
Brain - anatomy & histology
Brain Mapping
Child
Female
Humans
Language Development
Magnetic Resonance Imaging - methods
Male
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The potential benefits of functional magnetic resonance imaging (MRI) for the investigation of normal development have been limited by difficulties in its use with children. We describe the practical aspects, including failure rates, involved in conducting large-scale functional MRI studies with normal children. Two hundred and nine healthy children between the ages of 5 and 18 years participated in a functional MRI study of language development. Reliable activation maps were obtained across the age range. Younger children had significantly higher failure rates than older children and adolescents. It is concluded that it is feasible to conduct large-scale functional MRI studies of children as young as 5 years old. These findings can be used by other research groups to guide study design and plans for recruitment of young subjects. (J Child Neurol 2002;17:885—889).
ISSN:0883-0738
1708-8283
DOI:10.1177/08830738020170122201