Epithelioid angiosarcoma of the adrenal gland with cytokeratin expression report of a case with accompanying mesenteric fibromatosis

A case report of epithelioid adrenal angiosarcoma is presented. Tumor cells showed expression of cytokeratin, Factor VIII‐related antigen, Ulex europaeus agglutinin‐I, and vimentin. The patient also was found to have mesenteric fibromatosis (abdominal desmoid tumor) and an elevated serum level of es...

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Bibliographic Details
Published in:Cancer 1992-04, Vol.69 (7), p.1808-1812
Main Authors: Ben‐Izhak, Ofer, Auslander, Lya, Rabinson, Suzana, Lichtig, Chaim, Sternberg, Ahud
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - blood
Adrenal Gland Neoplasms - chemistry
Adrenal Gland Neoplasms - pathology
Adult
Estradiol - blood
Fibroma - blood
Fibroma - chemistry
Fibroma - pathology
Hemangiosarcoma - blood
Hemangiosarcoma - chemistry
Hemangiosarcoma - pathology
Humans
Immunohistochemistry
Keratins - analysis
Keratins - physiology
Male
Mesentery - pathology
Peritoneal Neoplasms - blood
Peritoneal Neoplasms - chemistry
Peritoneal Neoplasms - pathology
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Summary:A case report of epithelioid adrenal angiosarcoma is presented. Tumor cells showed expression of cytokeratin, Factor VIII‐related antigen, Ulex europaeus agglutinin‐I, and vimentin. The patient also was found to have mesenteric fibromatosis (abdominal desmoid tumor) and an elevated serum level of estradiol. The authors discuss the unique appearance of these rare tumors, their relationship to hyperestrinism, and review the recent data in the literature showing cytokeratin expression by malignant epithelioid vascular tumors.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19920401)69:7<1808::AID-CNCR2820690724>3.0.CO;2-E