5H-Furan-2-ones from fungal cultures of Aporpium caryae

Four furanones 1-4 with an unusual skeleton containing an acetylene unit, named aporpinones, were isolated from the culture of the basidiomycete Aporpium caryae and their structures were elucidated by spectroscopic methods. Compounds 3 and 4 showed weak to moderate antibacterial activity against Bac...

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Bibliographic Details
Published in:Phytochemistry (Oxford) 2003, Vol.62 (2), p.239-242
Main Authors: LEVY, Laura M, CABRERA, Gabriela M, WRIGHT, Jorge E, SELDES, Alicia M
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - analysis
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - pharmacology
Bacillus subtilis - drug effects
Basidiomycota - chemistry
Biological and medical sciences
Chemical constitution
Escherichia coli - drug effects
Fundamental and applied biological sciences. Psychology
Furans - analysis
Furans - isolation & purification
Furans - pharmacology
General pharmacology
Medical sciences
Molecular Structure
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant physiology and development
Staphylococcus aureus - drug effects
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Summary:Four furanones 1-4 with an unusual skeleton containing an acetylene unit, named aporpinones, were isolated from the culture of the basidiomycete Aporpium caryae and their structures were elucidated by spectroscopic methods. Compounds 3 and 4 showed weak to moderate antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli.
ISSN:0031-9422
1873-3700
DOI:10.1016/S0031-9422(02)00455-7