Epidemiological Features of Pertussis in the United States, 1980–1989

From 1980 through 1989, 27,826 cases of pertussis were reported to the Centers for Disease Control, for an average annual crude incidence of 1.2 cases/100,000 population. The incidence of reported disease increased in all age groups during this period, but the increase was disproportionately large a...

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Bibliographic Details
Published in:Clinical infectious diseases 1992-03, Vol.14 (3), p.708-719
Main Authors: Farizo, Karen M., Cochi, Stephen L., Zell, Elizabeth R., Brink, Edward W., Wassilak, Steven G., Patriarca, Peter A.
Format: Article
Language:English
Subjects:
Age
Age Factors
Age groups
Bordetella pertussis
Children
Cough
Diphtheria-Tetanus-Pertussis Vaccine
Disease Outbreaks
Epidemiology
Erythromycin - therapeutic use
Humans
Incidence
Infants
Notifiable diseases
Review Articles
Seasons
Sex Factors
Surveillance
United States - epidemiology
Vaccination
Whooping cough
Whooping Cough - complications
Whooping Cough - drug therapy
Whooping Cough - epidemiology
Whooping Cough - prevention & control
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Summary:From 1980 through 1989, 27,826 cases of pertussis were reported to the Centers for Disease Control, for an average annual crude incidence of 1.2 cases/100,000 population. The incidence of reported disease increased in all age groups during this period, but the increase was disproportionately large among adolescents and adults. Infants between 1 and 2 months of age were at highest risk for pertussis (average annual incidence, 62.8/100,000). Infants < 2 months of age had the highest reported rates of pertussis-associated hospitalization (82%), pneumonia (25%), seizures (4%), encephalopathy (1%), and death (1%). Rates of complication were generally higher among unvaccinated children than among those who had received three or more doses of diphtheria-tetanus-pertussis vaccine; 64% of children 3 months to 4 years of age who had reported cases of pertussis had not been immunized appropriately for their age. Whereas control of pertussis in the United States may be further improved through increased levels of diphtheriatetanus-pertussis vaccination among eligible infants and children, the use of acellular vaccines in adolescents and adults may also be needed to reduce the burden of pertussis in very young infants.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/14.3.708