Plasma Concentrations of Vitamins A and E and Carotenoids in Alzheimer's Disease

In a case/control study, serum concentrations of vitamins A and E and major carotenoids were determined in patients with Alzheimer's disease, multi-infarct dementia and control subjects. The results showed that both Alzheimer's and multi-infarct dementia patients had significantly lower le...

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Bibliographic Details
Published in:Age and ageing 1992-03, Vol.21 (2), p.91-94
Main Authors: ZAMAN, Z., ROCHE, S., FIELDEN, P., FROST, P. G., NIRIELLA, D. C., CAYLEY, A. C. D.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alzheimer Disease - blood
Alzheimer Disease - diagnosis
Alzheimer Disease - etiology
Alzheimer's disease
beta Carotene
Carotenoids - blood
Dementia, Multi-Infarct - blood
Dementia, Multi-Infarct - diagnosis
Female
Free Radicals
Humans
Male
Medical research
Reference Values
Vitamin A - blood
Vitamin E - blood
Vitamins
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Summary:In a case/control study, serum concentrations of vitamins A and E and major carotenoids were determined in patients with Alzheimer's disease, multi-infarct dementia and control subjects. The results showed that both Alzheimer's and multi-infarct dementia patients had significantly lower levels of vitamin E and β-carotene than controls (vitamin E: 18.65±3.62 μmol/l in Alzheimer's disease and 15.80±6.93 μmol/l in multi-infarct dementia versus 30.03±12.03 μmol/l in controls; β-carotene
ISSN:0002-0729
1468-2834
DOI:10.1093/ageing/21.2.91