Normative study of age variation in salivary progesterone profiles

Daily luteal progesterone levels were measured for 124 regularly menstruating women, aged 18–44, by radioimmunoassay of steroid levels in saliva. A consistent pattern of age variation in luteal function was found, with the lowest levels of progesterone in the 18–19-year-old and 40–44-year-old groups...

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Bibliographic Details
Published in:Journal of biosocial science 1992-04, Vol.24 (2), p.233-244
Main Authors: Lipson, S. F., Ellison, P. T.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age distribution
Biological and medical sciences
Female
Fundamental and applied biological sciences. Psychology
Hormone metabolism and regulation
Humans
Luteal Phase - physiology
Mammalian female genital system
Menstrual Cycle - physiology
Ovulation - physiology
Population
Progesterone - metabolism
Reference Values
Saliva - metabolism
Vertebrates: reproduction
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Summary:Daily luteal progesterone levels were measured for 124 regularly menstruating women, aged 18–44, by radioimmunoassay of steroid levels in saliva. A consistent pattern of age variation in luteal function was found, with the lowest levels of progesterone in the 18–19-year-old and 40–44-year-old groups, the highest values in the 25–34 year olds, and intermediate values in the 20–24 and 35–39-year-old groups. The striking similarity of this pattern of age variation with empirically and theoretically generated curves of apparent fecundability, suggests that age-related changes in ovarian function may underlie observed age variation in fecundability.
ISSN:0021-9320
1469-7599
DOI:10.1017/S0021932000019751