A Diagnostic Imaging Challenge Abscess-like Uptake of In-111 Leukocytes by Hepatocellular Carcinoma

An accurate and definitive distinction between liver abscess and hepatocellular carcinoma in patients with chronic alcoholic liver disease poses a significant diagnostic and therapeutic challenge for the clinician, but it is of the utmost importance because of significant differences in management a...

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Bibliographic Details
Published in:Clinical nuclear medicine 1992-05, Vol.17 (5), p.416-416
Main Authors: VIJAYAKUMAR, VANI, BEKERMAN, CARLOS, CHOWDHURY, LOKENDRA N
Format: Article
Language:English
Subjects:
Aged
Carcinoma, Hepatocellular - diagnostic imaging
Diagnosis, Differential
Humans
Indium Radioisotopes
Leukocytes
Liver Abscess - diagnostic imaging
Liver Neoplasms - diagnostic imaging
Male
Radionuclide Imaging
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Summary:An accurate and definitive distinction between liver abscess and hepatocellular carcinoma in patients with chronic alcoholic liver disease poses a significant diagnostic and therapeutic challenge for the clinician, but it is of the utmost importance because of significant differences in management and prognosis. The role of the In-111 leukocyte scan in the localization of areas of infection is well established; however, uptake by a tumor that resembles uptake in an abscess can also occur. The authors present a case of a proved hepatocellular carcinoma in which the uptake of In-111 granulocytes mimicked that in an abscess. Thus, cautious interpretation of In-111 leukocyte imaging is warranted in patients with underlying factors predisposing to neoplastic conditions.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199205000-00022