Combining low inspired oxygen and carbon dioxide during mechanical ventilation for the Norwood procedure

Summary Background: Staged reconstruction has become the preferred approach for treating neonates with hypoplastic left heart syndrome (HLHS). The haemodynamic instability of a single ventricle providing blood flow in parallel to the systemic and the pulmonary circulation, combined with the effects...

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Bibliographic Details
Published in:Pediatric anesthesia 2003-01, Vol.13 (1), p.58-62
Main Authors: Keidan, Ilan, Mishaly, David, Berkenstadt, Haim, Perel, Azriel
Format: Article
Language:English
Subjects:
Anesthesia
Anesthesia depending on type of surgery
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
carbon dioxide
Carbon Dioxide - therapeutic use
Cardiac Surgical Procedures
Humans
hypoplastic left heart syndrome
Hypoplastic Left Heart Syndrome - surgery
Infant, Newborn
low inspired oxygen
mechanical ventilation
Medical sciences
Norwood procedure
Oxygen Inhalation Therapy
Prospective Studies
Respiration, Artificial - methods
single-ventricle physiology
Thoracic and cardiovascular surgery. Cardiopulmonary bypass
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Summary:Summary Background: Staged reconstruction has become the preferred approach for treating neonates with hypoplastic left heart syndrome (HLHS). The haemodynamic instability of a single ventricle providing blood flow in parallel to the systemic and the pulmonary circulation, combined with the effects of cardiopulmonary bypass (CPB), results in precarious perioperative conditions. The two ventilatory manoeuvres commonly used for increasing pulmonary vascular resistance are (i) decreasing the fraction of inspired oxygen to
ISSN:1155-5645
1460-9592
DOI:10.1046/j.1460-9592.2003.00975.x