Cytokines during early pregnancy of mammals: a review

This article reviews the function of cytokines during early pregnancy of mammals including the human species. Investigations concerning conceptus and other secretory proteins, their meaning for maternal recognition and maintenance of pregnancy, fetal and placental growth and differentiation, adhesio...

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Bibliographic Details
Published in:Animal reproduction science 2003-01, Vol.75 (1), p.73-94
Main Author: Schäfer-Somi, S
Format: Article
Language:English
Subjects:
Animals
Chaperonin 10
Cytokines
Cytokines - immunology
Cytokines - physiology
Embryo Implantation - immunology
Embryo Implantation - physiology
Female
Growth factors
Growth Substances - immunology
Growth Substances - physiology
Humans
Immunology
Implantation
Mammals - immunology
Mammals - physiology
Peptides - immunology
Peptides - physiology
Placenta - immunology
Placenta - physiology
Pregnancy
Pregnancy - immunology
Pregnancy - physiology
Pregnancy Maintenance - immunology
Pregnancy Maintenance - physiology
Pregnancy Proteins
Pregnancy, Animal - immunology
Pregnancy, Animal - physiology
Species Specificity
Suppressor Factors, Immunologic
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Summary:This article reviews the function of cytokines during early pregnancy of mammals including the human species. Investigations concerning conceptus and other secretory proteins, their meaning for maternal recognition and maintenance of pregnancy, fetal and placental growth and differentiation, adhesion, invasion and implantation are discussed, and differences between laboratory rodents, carnivores, artiodactyls, horses and human beings elucidated and summarized. Finally topics that might be of interest for further research are emphasized.
ISSN:0378-4320
1873-2232
DOI:10.1016/S0378-4320(02)00222-1