Distinct Responses of Interleukin-6 and Other Laboratory Parameters to Treatment in a Patient with Polyarteritis Nodosa—A Case Report

The authors describe a patient in whom the serum levels of interleukin-6 (IL-6) and other laboratory parameters were monitored. The IL-6 and C-reac tive protein (CRP) levels, which were extremely high before treatment, declined rapidly with administration of prednisolone. Rheumatoid factor, IgG, and...

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Bibliographic Details
Published in:Angiology 1992-06, Vol.43 (6), p.512-516
Main Authors: Nakahama, Hajime, Okada, Mitsunori, Miyazaki, Mutsuo, Imai, Nobuyuki, Yokokawa, Tomoko, Kubori, Shujiro
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Bones, joints and connective tissue. Antiinflammatory agents
C-Reactive Protein - analysis
Humans
Immunoglobulin G - analysis
Interleukin-6 - blood
Leukocyte Count - drug effects
Male
Medical sciences
Pharmacology. Drug treatments
Platelet Count - drug effects
Polyarteritis Nodosa - blood
Polyarteritis Nodosa - drug therapy
Polyarteritis Nodosa - immunology
Prednisolone - pharmacology
Prednisolone - therapeutic use
Rheumatoid Factor - blood
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Summary:The authors describe a patient in whom the serum levels of interleukin-6 (IL-6) and other laboratory parameters were monitored. The IL-6 and C-reac tive protein (CRP) levels, which were extremely high before treatment, declined rapidly with administration of prednisolone. Rheumatoid factor, IgG, and platelets count declined more gradually. Thus, determination of the serum IL-6 level might be useful in diagnosing and monitoring polyarteritis nodosa.
ISSN:0003-3197
1940-1574
DOI:10.1177/000331979204300610