The Xenopus arx gene is expressed in the developing rostral forebrain

The human aristaless-related homeobox ( ARX) gene is mutated in several patients with X-linked mental retardation and/or other neurologic pathologies. We report the isolation and expression pattern of a Xenopus arx gene. Similar to other vertebrate arx genes, Xenopus arx is expressed in the developi...

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Bibliographic Details
Published in:Development genes and evolution 2003-01, Vol.212 (12), p.608-612
Main Authors: El-Hodiri, Heithem M, Qi, Xiu-Lan, Seufert, Daniel W
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
arx gene
Freshwater
Gene Expression Regulation, Developmental
Genes, Homeobox
Homeodomain Proteins - genetics
Homeodomain Proteins - metabolism
Molecular Sequence Data
Prosencephalon - embryology
Prosencephalon - metabolism
Sequence Homology, Amino Acid
Xenopus
Xenopus - genetics
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Summary:The human aristaless-related homeobox ( ARX) gene is mutated in several patients with X-linked mental retardation and/or other neurologic pathologies. We report the isolation and expression pattern of a Xenopus arx gene. Similar to other vertebrate arx genes, Xenopus arx is expressed in the developing telencephalon, diencephalon, and floor plate.
ISSN:0949-944X
1432-041X
DOI:10.1007/s00427-002-0282-8