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Region-Specific Apoptosis Limits Neural Stem Cell Proliferation
Regulation of stem cell division is of particular interest, both for studies of development and for stem cell therapeutics. In this issue of Neuron, Bello et al. show that the number of divisions of Drosophila neural stem cells is limited, in a region-specific manner, by regulated apoptosis in respo...
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Published in: | Neuron 2003-01, Vol.37 (2), p.185-187 |
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container_title | Neuron |
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creator | Brand, Andrea H. van Roessel, Peter J. |
description | Regulation of stem cell division is of particular interest, both for studies of development and for stem cell therapeutics. In this issue of
Neuron, Bello et al. show that the number of divisions of
Drosophila neural stem cells is limited, in a region-specific manner, by regulated apoptosis in response to a pulse of expression of the Hox gene
abdominal-A (
abdA). |
doi_str_mv | 10.1016/S0896-6273(03)00026-6 |
format | article |
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source | BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS |
subjects | Abdomen Animals Apoptosis Apoptosis - physiology Cell cycle Cell Division Cell Lineage Drosophila Mitosis - physiology Neurons - physiology Stem cells Stem Cells - physiology |
title | Region-Specific Apoptosis Limits Neural Stem Cell Proliferation |
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