Efficient Ring-Opening Reaction of Epoxides and Aziridines Promoted by Tributylphosphine in Water

Tributylphosphine was found to be an effective promoting reagent for the ring-opening reaction of various epoxides and aziridines with nucleophile to produce corresponding anti-bifunctional products in moderate to excellent yields in water.

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Bibliographic Details
Published in:Journal of organic chemistry 2003-02, Vol.68 (3), p.726-730
Main Authors: Fan, Ren-Hua, Hou, Xue-Long
Format: Article
Language:English
Subjects:
Aliphatic compounds
Chemistry
Exact sciences and technology
Organic chemistry
Preparations and properties
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Description
Summary:Tributylphosphine was found to be an effective promoting reagent for the ring-opening reaction of various epoxides and aziridines with nucleophile to produce corresponding anti-bifunctional products in moderate to excellent yields in water.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo025983s