Patterns of Genetic Variation in Native America

Allele frequencies from seven polymorphic red cell antigen loci (ABO, Rh, MN, S, P, Duffy, and Diego) were examined in 144 Native American populations. Mean genetic distances (Nei's D) and the fixation index F ST are approximately equal for the North and South American samples but are reduced i...

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Bibliographic Details
Published in:Human biology 1992-06, Vol.64 (3), p.417-434
Main Authors: O'ROURKE, DENNIS H., MOBARRY, ANNE, SUAREZ, BRIAN K.
Format: Article
Language:English
Subjects:
Blood
Blood Group Antigens - genetics
Demographic aspects
Evolutionary genetics
Gene Frequency
Genetic aspects
Genetic mapping
Genetic Variation
Genetics
Genetics, Population
Geography
Hemoglobin polymorphisms
Hemoglobins
Human genetics
Humans
Indians, Central American - genetics
Indians, North American - genetics
Indians, South American - genetics
Native Americans
Native North Americans
Population genetics
Population geography
Variation (Biology)
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Summary:Allele frequencies from seven polymorphic red cell antigen loci (ABO, Rh, MN, S, P, Duffy, and Diego) were examined in 144 Native American populations. Mean genetic distances (Nei's D) and the fixation index F ST are approximately equal for the North and South American samples but are reduced in the Central American geographic area. The relationship between genetic distance and geographic distance differs markedly across geographic areas. The correlation between geographic distance and genetic distance for the North and Central American data is twice as large as that observed for the South American samples. This geographic difference is confirmed in spatial autocorrelation analyses; no geographic structure is apparent in the South American data but geographic structure is prominent in North and Central American samples. These results confirm earlier observations regarding differences between North and South American gene frequency patterns.
ISSN:0018-7143
1534-6617