Lethal midline granuloma: impact of imaging studies on the investigation and management of destructive mid facial disease in 13 patients

In 13 patients presenting as lethal midline granuloma (LMG), computed tomography proved essential for determining the extent of the disease, guiding biopsy and planning radiotherapy. Magnetic resonance imaging (MRI) was also helpful for the latter, because it could distinguish fluid retained within...

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Bibliographic Details
Published in:Neuroradiology 1992, Vol.34 (2), p.155-161
Main Authors: Marsot-Dupuch, K, Cabane, J, Raveau, V, Aoun, N, Tubiana, J M
Format: Article
Language:English
Subjects:
Adult
Aged
Diagnosis, Differential
Facial Neoplasms - diagnosis
Facial Neoplasms - pathology
Facial Neoplasms - radiotherapy
Female
Follow-Up Studies
Granuloma, Lethal Midline - diagnosis
Granuloma, Lethal Midline - pathology
Granuloma, Lethal Midline - radiotherapy
Humans
Lymphoma, T-Cell - diagnosis
Lymphoma, T-Cell - pathology
Lymphoma, T-Cell - radiotherapy
Magnetic Resonance Imaging
Male
Middle Aged
Tomography, X-Ray Computed
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Summary:In 13 patients presenting as lethal midline granuloma (LMG), computed tomography proved essential for determining the extent of the disease, guiding biopsy and planning radiotherapy. Magnetic resonance imaging (MRI) was also helpful for the latter, because it could distinguish fluid retained within the paranasal sinuses from solid masses and tumour from granulation tissue; it was of little value for detecting bone lysis. Eight of the 13 patients proved to have T-cell lymphoma, two had Crohn's disease, in one the lesion was factitious and two had granulomas without diagnostic histological features.
ISSN:0028-3940
1432-1920
DOI:10.1007/BF00588164