Stevens‐Johnson Syndrome with Idiopathic Thrombocytopenic Purpura Treated with Dexamethasone Pulse Therapy

Stevens‐Johnson syndrome (SJS) is a severe, episodic, acute, mucocutaneous hypersensitivity reaction often caused by drugs. We herewith report a case of SJS with idiopathic thrombocytopenic purpura (ITP) that did not respond to daily oral prednisolone therapy. When treated with dexamethasone pulse t...

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Bibliographic Details
Published in:Journal of dermatology 2003-01, Vol.30 (1), p.54-58
Main Authors: Barman, Krishna Deb, Verma, Kaushal K., Agrawal, Sudha, Agarwalla, Arun, Rijal, Arpana
Format: Article
Language:English
Subjects:
Adult
Anti-Inflammatory Agents - administration & dosage
Anti-Inflammatory Agents - therapeutic use
Dexamethasone - administration & dosage
Dexamethasone - therapeutic use
dexamethasone pulse therapy
Diagnosis, Differential
Humans
idiopathic thrombocytopenic purpura
Infusions, Intravenous
Lower Extremity
Male
Pulse Therapy, Drug
Purpura, Thrombocytopenic, Idiopathic - complications
Scrotum
Stevens-Johnson Syndrome - complications
Stevens-Johnson Syndrome - diagnosis
Stevens-Johnson Syndrome - drug therapy
Stevens-Johnson Syndrome - pathology
Stevens‐Johnson syndrome
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Summary:Stevens‐Johnson syndrome (SJS) is a severe, episodic, acute, mucocutaneous hypersensitivity reaction often caused by drugs. We herewith report a case of SJS with idiopathic thrombocytopenic purpura (ITP) that did not respond to daily oral prednisolone therapy. When treated with dexamethasone pulse therapy, the response was found to be very good. Therefore, we concluded that dexamethasone pulse therapy can be a good and an effective alternative therapy for treatment of such patients. However, to establish its role, further trials in more patients are needed.
ISSN:0385-2407
1346-8138
DOI:10.1111/j.1346-8138.2003.tb00333.x