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Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase
Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, V...
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Published in: | FEBS letters 1992-06, Vol.304 (1), p.9-11 |
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container_title | FEBS letters |
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creator | Lipkin, V.M. Surina, E.A. Petukhova, G.V. Petrov, V.M. Mirzoeva, S.F. Rakitina, T.V. |
description | Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in
Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664–678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM. |
doi_str_mv | 10.1016/0014-5793(92)80577-4 |
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Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664–678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.</description><identifier>ISSN: 0014-5793</identifier><identifier>EISSN: 1873-3468</identifier><identifier>DOI: 10.1016/0014-5793(92)80577-4</identifier><identifier>PMID: 1618305</identifier><identifier>CODEN: FEBLAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adenylate cyclase ; Adenylyl Cyclases - genetics ; Amino Acid Sequence ; Analytical, structural and metabolic biochemistry ; Animals ; Biological and medical sciences ; bovine serum albumin ; brain ; BSA ; Cattle ; Cell Adhesion Molecules, Neuronal - genetics ; Cloning, Molecular ; ELISA ; enzyme-linked immunosorbent assay ; Enzymes and enzyme inhibitors ; Fundamental and applied biological sciences. Psychology ; Humans ; interaction ; Lyases ; man ; Molecular Sequence Data ; N-CAM ; NCAM protein ; Neural cell adhesion molecule ; Sequence Homology, Nucleic Acid ; Xenopus laevis ; γ-subunit of cGMP phosphodiesterase ; γPDE</subject><ispartof>FEBS letters, 1992-06, Vol.304 (1), p.9-11</ispartof><rights>1992</rights><rights>FEBS Letters 304 (1992) 1873-3468 © 2015 Federation of European Biochemical Societies</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4804-2c512502eef03202a39acd4d94a8eafb1bf66c7caab80beee3246471dc1548673</citedby><cites>FETCH-LOGICAL-c4804-2c512502eef03202a39acd4d94a8eafb1bf66c7caab80beee3246471dc1548673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0014579392805774$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3549,27924,27925,45780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5297624$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1618305$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lipkin, V.M.</creatorcontrib><creatorcontrib>Surina, E.A.</creatorcontrib><creatorcontrib>Petukhova, G.V.</creatorcontrib><creatorcontrib>Petrov, V.M.</creatorcontrib><creatorcontrib>Mirzoeva, S.F.</creatorcontrib><creatorcontrib>Rakitina, T.V.</creatorcontrib><title>Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase</title><title>FEBS letters</title><addtitle>FEBS Lett</addtitle><description>Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in
Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664–678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.</description><subject>Adenylate cyclase</subject><subject>Adenylyl Cyclases - genetics</subject><subject>Amino Acid Sequence</subject><subject>Analytical, structural and metabolic biochemistry</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>bovine serum albumin</subject><subject>brain</subject><subject>BSA</subject><subject>Cattle</subject><subject>Cell Adhesion Molecules, Neuronal - genetics</subject><subject>Cloning, Molecular</subject><subject>ELISA</subject><subject>enzyme-linked immunosorbent assay</subject><subject>Enzymes and enzyme inhibitors</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>interaction</subject><subject>Lyases</subject><subject>man</subject><subject>Molecular Sequence Data</subject><subject>N-CAM</subject><subject>NCAM protein</subject><subject>Neural cell adhesion molecule</subject><subject>Sequence Homology, Nucleic Acid</subject><subject>Xenopus laevis</subject><subject>γ-subunit of cGMP phosphodiesterase</subject><subject>γPDE</subject><issn>0014-5793</issn><issn>1873-3468</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><recordid>eNqNkEtP3DAUha2qCAbaf1CkLKoKFqF-xY8NEowYQKJUqtq15Tg3GiNPMtiTovn3xGQEO9qV5Xu-c659EPpC8BnBRHzHmPCykpqdaHqqcCVlyT-gGVGSlYwL9RHNXpEDdJjSAx7viuh9tE8EUQxXM3T_C4Ld-L5LS78u-rboYIg2FA5CKGyzhDRqxaoP4IYAqTi5L-cXP9Jp8eQ3yxGAbjv6oXBbF2yCT2ivtSHB5915hP4srn7Pb8q7n9e384u70nGFeUldRWiFKUCLGcXUMm1dwxvNrQLb1qRuhXDSWVsrXAMAo1xwSRpHKq6EZEfo25S7jv3jAGljVj7lN9sO-iEZyTDTlSD_BIngnGGZQT6BLvYpRWjNOvqVjVtDsMl9m1ymyWUaTc1L34aPtuNd_lCvoHkzTQWP-tedbpOzoY22cz69YhXVUtAcs5iwJx9g-1-rzeLqkmYhzzV9meag8ykIxvb_eogmOQ-dg8ZHcBvT9P79Dz0D066uBw</recordid><startdate>19920608</startdate><enddate>19920608</enddate><creator>Lipkin, V.M.</creator><creator>Surina, E.A.</creator><creator>Petukhova, G.V.</creator><creator>Petrov, V.M.</creator><creator>Mirzoeva, S.F.</creator><creator>Rakitina, T.V.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19920608</creationdate><title>Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase</title><author>Lipkin, V.M. ; Surina, E.A. ; Petukhova, G.V. ; Petrov, V.M. ; Mirzoeva, S.F. ; Rakitina, T.V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4804-2c512502eef03202a39acd4d94a8eafb1bf66c7caab80beee3246471dc1548673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adenylate cyclase</topic><topic>Adenylyl Cyclases - genetics</topic><topic>Amino Acid Sequence</topic><topic>Analytical, structural and metabolic biochemistry</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>bovine serum albumin</topic><topic>brain</topic><topic>BSA</topic><topic>Cattle</topic><topic>Cell Adhesion Molecules, Neuronal - genetics</topic><topic>Cloning, Molecular</topic><topic>ELISA</topic><topic>enzyme-linked immunosorbent assay</topic><topic>Enzymes and enzyme inhibitors</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>interaction</topic><topic>Lyases</topic><topic>man</topic><topic>Molecular Sequence Data</topic><topic>N-CAM</topic><topic>NCAM protein</topic><topic>Neural cell adhesion molecule</topic><topic>Sequence Homology, Nucleic Acid</topic><topic>Xenopus laevis</topic><topic>γ-subunit of cGMP phosphodiesterase</topic><topic>γPDE</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lipkin, V.M.</creatorcontrib><creatorcontrib>Surina, E.A.</creatorcontrib><creatorcontrib>Petukhova, G.V.</creatorcontrib><creatorcontrib>Petrov, V.M.</creatorcontrib><creatorcontrib>Mirzoeva, S.F.</creatorcontrib><creatorcontrib>Rakitina, T.V.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>FEBS letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lipkin, V.M.</au><au>Surina, E.A.</au><au>Petukhova, G.V.</au><au>Petrov, V.M.</au><au>Mirzoeva, S.F.</au><au>Rakitina, T.V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase</atitle><jtitle>FEBS letters</jtitle><addtitle>FEBS Lett</addtitle><date>1992-06-08</date><risdate>1992</risdate><volume>304</volume><issue>1</issue><spage>9</spage><epage>11</epage><pages>9-11</pages><issn>0014-5793</issn><eissn>1873-3468</eissn><coden>FEBLAL</coden><abstract>Bovine brain cDNA cloned earlier and attributed to calmodulin-independent adenylate cyclase encodes the neural cell adhesion molecule (N-CAM). The expression of N-CAM mRNA in
Xenopus laevis oocytes increases their basal adenylate cyclase activity. Polyclonal antibodies against synthetic peptide A, VAENQQGKSKAAHFV (664–678 amino acid residues of bovine N-CAM), containing sequence AXXXXGKS which is homologous to the nucleotide-binding consensus sequence GXXXXGKS, inhibit the adenylate cyclase activity. A close relationship appears to exist between adenylate cyclase and N-CAM.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>1618305</pmid><doi>10.1016/0014-5793(92)80577-4</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adenylate cyclase Adenylyl Cyclases - genetics Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Biological and medical sciences bovine serum albumin brain BSA Cattle Cell Adhesion Molecules, Neuronal - genetics Cloning, Molecular ELISA enzyme-linked immunosorbent assay Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Humans interaction Lyases man Molecular Sequence Data N-CAM NCAM protein Neural cell adhesion molecule Sequence Homology, Nucleic Acid Xenopus laevis γ-subunit of cGMP phosphodiesterase γPDE |
title | Relationship of neural cell adhesion molecules (N-CAMs) with adenylate cyclase |
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