Nodal yield in neck dissection and the likelihood of metastases

Objectives: The purpose of this study was to begin investigating the relationship between nodal yield in neck dissection and the likelihood of finding cervical metastases in T1 and T2 head and neck squamous cell carcinoma (HNSCC). No clinical implications are drawn from this preliminary work. Study...

Full description

Saved in:
Bibliographic Details
Published in:Otolaryngology-head and neck surgery 2003-02, Vol.128 (2), p.185-190
Main Authors: Agrama, Mark T, Reiter, David, Cunnane, Mary F, Topham, Allan, Keane, William M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Female
Head and Neck Neoplasms - secondary
Humans
Hypopharyngeal Neoplasms - pathology
Hypopharyngeal Neoplasms - surgery
Lymph Node Excision - methods
Male
Middle Aged
Mouth Neoplasms - pathology
Mouth Neoplasms - surgery
Multivariate Analysis
Neck Dissection - methods
Neoplasm Staging
Oropharyngeal Neoplasms - pathology
Oropharyngeal Neoplasms - surgery
Retrospective Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives: The purpose of this study was to begin investigating the relationship between nodal yield in neck dissection and the likelihood of finding cervical metastases in T1 and T2 head and neck squamous cell carcinoma (HNSCC). No clinical implications are drawn from this preliminary work. Study Design and Setting: This study was a retrospective analysis of 564 patients with T1 and T2 HNSCC of the oral cavity, oropharynx, or hypopharynx from the National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program registry. A multivariate analysis was performed to evaluate the relationship between nodal yield in neck dissection and the discovery of cervical metastases. Other independent factors included in the analysis were gender, age, race, and primary site of tumor. Results: Compared with nodal yield < 13, cervical metastases were more likely to be found for nodal yield 21-28 (P < 0.001, odds ratio [OR] = 3.68), 29-40 (P = 0.021, OR = 1.98), and >40 (P < 0.001, OR = 3.52). Increased age, male sex, and oropharynx and hypopharynx primaries were also associated with a significantly increased likelihood of finding cervical metastases. Conclusion: In T1 and T2 cases of HNSCC, nodal yield >20, increased age, male sex, and primary site correspond with an increased likelihood of finding cervical metastases. (Otolaryngol Head Neck Surg 2003;128:185-90.)
ISSN:0194-5998
1097-6817
DOI:10.1067/mhn.2003.67