Impact of abnormal nocturnal blood pressure fall on vascular function

It is well known that nondipping pattern of arterial hypertension has a harmful effect on target organs such as the brain, heart, and kidneys. However, it remains uncertain whether abnormal dipping patterns of nocturnal blood pressure (BP), such as extreme and reverse dipping, influence vascular fun...

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Bibliographic Details
Published in:American journal of hypertension 2003-03, Vol.16 (3), p.209-213
Main Authors: Marinakis, Andreas G, Vyssoulis, Gregory P, Michaelides, Andreas P, Karpanou, Eva A, Cokkinos, Dennis V, Toutouzas, Pavlos K
Format: Article
Language:English
Subjects:
Adult
Aged
Albuminuria - physiopathology
Albuminuria - urine
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure - physiology
Blood Pressure Monitoring, Ambulatory
Cardiology. Vascular system
Circadian Rhythm - physiology
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Creatinine - urine
extreme dippers
Female
Humans
Hypertension - diagnosis
Hypertension - physiopathology
Hypertension - urine
Male
Medical sciences
microalbuminuria
Middle Aged
Nondippers
reverse dippers
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Summary:It is well known that nondipping pattern of arterial hypertension has a harmful effect on target organs such as the brain, heart, and kidneys. However, it remains uncertain whether abnormal dipping patterns of nocturnal blood pressure (BP), such as extreme and reverse dipping, influence vascular function. This study comprised consecutive 2800 individuals (1554 men and 1246 women). All were nondiabetic and had uncomplicated, untreated essential sustained hypertension based on office measurements. After a 2-week wash-out period, 24-h ambulatory BP recordings were obtained and patients were classified by their nocturnal systolic BP fall (132 extreme dippers with >20% nocturnal systolic BP fall; 1235 dippers with >10% but 0% but
ISSN:0895-7061
1879-1905
1941-7225
DOI:10.1016/S0895-7061(02)03262-4