Evaluation of once daily treatment with cyclosporine for anal furunculosis in dogs

Twenty.four dogs with anal furunculosis were treated with cyclosporine once daily for 13 weeks at dosages of 1.5, 3.0, 5.0 or 7.5 mg/kg, and re.examined after six and 12 months. After 13 weeks the disease in six of the dogs was in remission, 11 were controlled or improved and seven had failed to res...

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Bibliographic Details
Published in:Veterinary record 2003-02, Vol.152 (8), p.225-229
Main Authors: Doust, R., Griffiths, L. G., Sullivan, M.
Format: Article
Language:English
Subjects:
Adjuvants, Immunologic - administration & dosage
Administration, Oral
adverse effects
Animals
Anus Diseases - drug therapy
Anus Diseases - pathology
cyclosporine
Cyclosporine - administration & dosage
Dog Diseases - drug therapy
Dog Diseases - pathology
Dogs
Dose-Response Relationship, Drug
Drug Administration Schedule
drug therapy
furunculosis
Furunculosis - drug therapy
Furunculosis - veterinary
remission
Treatment Outcome
vomiting
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Summary:Twenty.four dogs with anal furunculosis were treated with cyclosporine once daily for 13 weeks at dosages of 1.5, 3.0, 5.0 or 7.5 mg/kg, and re.examined after six and 12 months. After 13 weeks the disease in six of the dogs was in remission, 11 were controlled or improved and seven had failed to respond. The response of the dogs given the highest dose was significantly better than the response of the other groups taken together (P
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.152.8.225