The effect of body weight on the degree of blood velocity profile skewness in the aortic annulus in domestic pigs

We investigated the blood velocity profile in the aortic annulus (AA) in two groups of domestic pigs using epicardial Doppler echocardiography. The velocity profile skewness in terms of max/mean TVI (the ratio of maximal to cross-sectional mean time-velocity integral along the diameter) was 1.107 ±...

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Bibliographic Details
Published in:Laboratory animals (London) 2003-01, Vol.37 (1), p.72-80
Main Authors: Matre, K, Kvitting, P, Zhou, Y Q, Faerestrand, S
Format: Article
Language:English
Subjects:
Animals
Aorta - diagnostic imaging
Aorta - physiology
Blood Flow Velocity
Body Weight
False Positive Reactions
Swine - physiology
Ultrasonography, Doppler, Color
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Summary:We investigated the blood velocity profile in the aortic annulus (AA) in two groups of domestic pigs using epicardial Doppler echocardiography. The velocity profile skewness in terms of max/mean TVI (the ratio of maximal to cross-sectional mean time-velocity integral along the diameter) was 1.107 ± 0.01 in the small pigs (n = 10; body weight: 24.6 ± 0.8 kg) and 1.216 ± 0.026 in the large pigs (n = 8; body weight: 50.6 ± 2.5 kg) (P = 0.002). The velocity profile in the AA is more skewed in large animals than in small animals and the skewness in the larger animals is similar to that in normal adult humans. This study shows the importance of choosing animals of sufficient size if flow method investigations are to be performed. This is particularly important for ultrasound Doppler investigations based on a limited sample of velocities across the flow channel.
ISSN:0023-6772
1758-1117
DOI:10.1258/002367703762226728