PROSPECTIVE, CONTROLLED, DOUBLE-BLIND STUDY OF I.V. TENOXICAM FOR ANALGESIA AFTER THORACOTOMY

We have shown that a single i.v. dose of tenoxicam 20 mg, after thoracotomy, when compared with placebo in 20 patients (with one exclusion), was associated with a reduction in consumption of papaveretum, assessed by patient-controlled analgesia, of 2.2 mg h−1 (22%) to 4 h and 1.4mg h−1 (23%) to 12 h...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1992-07, Vol.69 (1), p.92-94
Main Authors: MERRY, A.F., WARDALL, G.J., CAMERON, R.J., PESKETT, M.J., WILD, C.J.
Format: Article
Language:English
Subjects:
Adult
Aged
Analgesia
Analgesia - methods
Analgesia, Patient-Controlled
Analgesics
Analgesics: non-steroidal
Anti-Inflammatory Agents, Non-Steroidal
Biological and medical sciences
Double-Blind Method
Female
Humans
Injections, Intravenous
Male
Medical sciences
Middle Aged
Neuropharmacology
Opium
Pain, Postoperative - drug therapy
patient-controlled
Pharmacology. Drug treatments
Piroxicam - analogs & derivatives
postoperative: on demand
Prospective Studies
Thoracotomy
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Summary:We have shown that a single i.v. dose of tenoxicam 20 mg, after thoracotomy, when compared with placebo in 20 patients (with one exclusion), was associated with a reduction in consumption of papaveretum, assessed by patient-controlled analgesia, of 2.2 mg h−1 (22%) to 4 h and 1.4mg h−1 (23%) to 12 h after operation (repeated measures analysis of variance: P < 0.01). There was no reduction from 12 to 24 h. There was no significant difference between groups in pain scores or in side effects.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/69.1.92