Molecular cladistic markers in New World monkey phylogeny (Platyrrhini, Primates)

Transpositions of primate-specific Alu elements were applied as molecular cladistic markers in a phylogenetic analysis of South American primates. Seventy-four human and platyrrhine loci containing intronic Alu elements were PCR screened in various New World monkeys and the human outgroup to detect...

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Bibliographic Details
Published in:Molecular phylogenetics and evolution 2003-03, Vol.26 (3), p.490-501
Main Authors: Singer, Silke S, Schmitz, Jürgen, Schwiegk, Claudia, Zischler, Hans
Format: Article
Language:English
Subjects:
Alu elements
Alu Elements - genetics
Animals
Aotus
Base Sequence
Callimico
Callithrix
Cebidae - classification
Cebidae - genetics
Cebuella
Cebus
DNA Primers
Genetic Markers - genetics
Introns
Molecular Sequence Data
Phylogeny
Polymorphism, Genetic
Saimiri
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Summary:Transpositions of primate-specific Alu elements were applied as molecular cladistic markers in a phylogenetic analysis of South American primates. Seventy-four human and platyrrhine loci containing intronic Alu elements were PCR screened in various New World monkeys and the human outgroup to detect the presence of orthologous retrotransposons informative of New World monkey phylogeny. Six loci revealed size polymorphism in the amplification pattern, indicating a shared derived character state due to the presence of orthologous Alu elements confirmed by subsequent sequencing. Three markers corroborate (1) New World monkey monophyly and one marker supports each of the following callitrichine relationships: (2) Callithrix and Cebuella are more closely related to each other than to any other callitrichine, (3) the callitrichines form a monophyletic clade including Callimico, and (4) the next living relatives to the callitrichines are Cebus, Saimiri, and Aotus.
ISSN:1055-7903
1095-9513
DOI:10.1016/S1055-7903(02)00312-3