Leukemia cutis presenting with fingertip hypertrophy

Patients with leukemia often manifest cutaneous findings, which include nonspecific lesions and specific leukemic infiltrates termed leukemia cutis. A case of leukemia cutis involving distal finger pads is reported and literature describing hand involvement of specific leukemic infiltrates is review...

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Bibliographic Details
Published in:Journal of cutaneous medicine and surgery 2003-01, Vol.7 (1), p.57-60
Main Authors: FREIMAN, Anatoli, MUBU, Channy Y, TRUDEL, Michel, BILLICK, Robin C
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Diagnosis, Differential
Female
Fingers - pathology
Hematologic and hematopoietic diseases
Humans
Hypertrophy
Leukemia - complications
Leukemia - pathology
Leukemia, Lymphocytic, Chronic, B-Cell - complications
Leukemia, Lymphocytic, Chronic, B-Cell - pathology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
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Description
Summary:Patients with leukemia often manifest cutaneous findings, which include nonspecific lesions and specific leukemic infiltrates termed leukemia cutis. A case of leukemia cutis involving distal finger pads is reported and literature describing hand involvement of specific leukemic infiltrates is reviewed. An 80-year-old woman with a 10-year history of chronic lymphocytic leukemia developed painful symmetric tumors of her distal finger pads. Histopathological examination of the biopsy specimen revealed infiltration by neoplastic lymphocytes. Only a few cases of leukemia cutis involving the hands have been reported in the literature, none with this particular presentation. The clinical and histopathologic features of leukemia cutis are reviewed. This case emphasizes the importance of obtaining a biopsy specimen for histopathological examination of any suspicious skin lesion in a patient with leukemia.
ISSN:1203-4754
1615-7109
DOI:10.1007/s10227-002-1162-6