Milk yields and hormone concentrations of Holstein cows in response to sometribove (somatotropin) treatment during the dry period

Holstein cows (n = 135) under commercial management were used to determine whether sometribove (recombinant methionyl bST, 25 mg/d) administered during the dry period affected milk yield during the ensuing lactation. Cows scheduled to begin lactations (greater than or equal to 2) during January to M...

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Bibliographic Details
Published in:Journal of dairy science 1992-07, Vol.75 (7), p.1883-1890
Main Authors: Bachman, K.C. (University of Florida, Gainesville), Wilfond, D.H, Head, H.H, Wilcox, C.J, Singh, M
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cattle - physiology
Female
Food industries
Fundamental and applied biological sciences. Psychology
Growth Hormone - administration & dosage
Growth Hormone - analogs & derivatives
Growth Hormone - pharmacology
HORMONAS PITUITARIAS
HORMONE HYPOPHYSAIRE
Hormones - administration & dosage
Hormones - blood
Hormones - pharmacology
Human Growth Hormone
Injections, Subcutaneous - veterinary
Insulin-Like Growth Factor I - analysis
INSULINA
INSULINE
LACTACION
LACTATION
Lactation - drug effects
Least-Squares Analysis
Mammary Glands, Animal - drug effects
Mammary Glands, Animal - secretion
Milk - secretion
Milk and cheese industries. Ice creams
PERIODE DE TARISSEMENT
PERIODO DE SECADO
PROLACTINA
PROLACTINE
Random Allocation
Recombinant Proteins - administration & dosage
Recombinant Proteins - pharmacology
Regression Analysis
RENDEMENT LAITIER
RENDIMIENTO LECHERO
SERUM SANGUIN
SUERO SANGUINEO
THYROXINE
TIROXINA
TRIIODOTHYRONINE
TRIIODOTIRONINA
VACAS LECHERAS
VACHE LAITIERE
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Summary:Holstein cows (n = 135) under commercial management were used to determine whether sometribove (recombinant methionyl bST, 25 mg/d) administered during the dry period affected milk yield during the ensuing lactation. Cows scheduled to begin lactations (greater than or equal to 2) during January to March were assigned randomly to treatments of sodium bicarbonate excipient (n = 67) or bST (25 mg/d, n = 68). Subcutaneous injections were given for 14 d, corresponding to d -21 to -7 relative to expected calving date. Days dry prior to first injection (64.0, 60.2) and number of injections received (13.9, 13.8) were similar for control and treatment groups, but days from last injection to calving (8.8, 7.1) differed. No differences in incidence of dystocia or udder edema were detected. Previous lactation yields were 8251 and 7952 kg, and yields for lactations following treatment were 8328 and 7852 kg, based on complete lactation data. Mean test date 3.5% FCM yields for control and treated groups during experimental lactation differed before (30.3 vs. 28.1 kg) but not after (29.5 vs. 28.4 kg) covariance adjustment for previous total lactation milk yield. Test of heterogeneity of regression provided no evidence that respective curves for FCM yield during lactation were not parallel or of different magnitude. Elevation of serum bST during 2 wk of the dry period resulted in no apparent increase in extent of mammogenesis or lactogenesis that was translated into an increase in milk yield
ISSN:0022-0302
1525-3198
DOI:10.3168/jds.S0022-0302(92)77948-X