In vitro screening of two Nigerian medicinal plants ( Vernonia amygdalina and Annona senegalensis) for anthelmintic activity

Vernonia amygdalina and Annona senegalensis, two plants used by local/smallholder livestock farmers in Nigeria as anthelmintic were screened for in vitro anthelmintic activity using Haemonchus contortus eggs. The extract of V. amygdalina did not show any significant activity at concentrations up to...

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Bibliographic Details
Published in:Veterinary parasitology 2003-04, Vol.113 (1), p.73-81
Main Authors: Alawa, C.B.I, Adamu, A.M, Gefu, J.O, Ajanusi, O.J, Abdu, P.A, Chiezey, N.P, Alawa, J.N, Bowman, D.D
Format: Article
Language:English
Subjects:
Animals
Annona - chemistry
Annona senegalensis
Anthelmintic
Anthelmintics - chemistry
Anthelmintics - isolation & purification
Anthelmintics - pharmacology
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Haemonchus - drug effects
Haemonchus contortus
Nigeria
Ovum - drug effects
Phytotherapy
Plant Bark - chemistry
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Leaves - chemistry
Plant Stems - chemistry
Plants, Medicinal - chemistry
Vernonia - chemistry
Vernonia amygdalina
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Summary:Vernonia amygdalina and Annona senegalensis, two plants used by local/smallholder livestock farmers in Nigeria as anthelmintic were screened for in vitro anthelmintic activity using Haemonchus contortus eggs. The extract of V. amygdalina did not show any significant activity at concentrations up to 11.2 mg/ml. The extract of A. senegalensis showed significant ( P
ISSN:0304-4017
1873-2550
DOI:10.1016/S0304-4017(03)00040-2