A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals

The results of studies conducted with a small field of view tomographic gamma camera based on a Position Sensitive Photomultiplier Tube are reported. The system has been used for the evaluation of radiopharmaceuticals in small animals. Phantom studies have shown a spatial resolution of 2 mm in plana...

Full description

Saved in:
Bibliographic Details
Published in:Applied radiation and isotopes 2003-04, Vol.58 (4), p.501-508
Main Authors: Loudos, G.K., Nikita, K.S., Giokaris, N.D., Styliaris, E., Archimandritis, S.C., Varvarigou, A.D., Papanicolas, C.N., Majewski, S., Weisenberger, D., Pani, R., Scopinaro, F., Uzunoglu, N.K., Maintas, D., Stefanis, K.
Format: Article
Language:English
Subjects:
Algorithms
Animals
Bombesin - pharmacokinetics
Gamma Cameras
High resolution
Image Processing, Computer-Assisted - instrumentation
Kidney - diagnostic imaging
Mice
Mice, Nude
Neoplasms, Experimental - diagnostic imaging
PSPMT
Radionuclide Imaging
Radiopharmaceutical studies
Radiopharmaceuticals - pharmacokinetics
Sensitivity and Specificity
Signal Processing, Computer-Assisted - instrumentation
Small animal imaging
SPECT
Technetium - chemistry
Technetium - pharmacokinetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The results of studies conducted with a small field of view tomographic gamma camera based on a Position Sensitive Photomultiplier Tube are reported. The system has been used for the evaluation of radiopharmaceuticals in small animals. Phantom studies have shown a spatial resolution of 2 mm in planar and 2–3 mm in tomographic imaging. Imaging studies in mice have been carried out both in 2D and 3D. Conventional radiopharmaceuticals have been used and the results have been compared with images from a clinically used system.
ISSN:0969-8043
1872-9800
DOI:10.1016/S0969-8043(03)00025-3