18F-Fluorodeoxyglucose-positron emission tomography: A new explorative perspective

18F-Fluorodeoxyglucose-positron emission tomography ( 18F-FDG-PET) is a new functional imaging technique available for clinical and experimental use. 18F-FDG-PET studies can be used for screening, localization and follow-up of hypermetabolic processes including malignancies, infections and autoimmun...

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Bibliographic Details
Published in:Experimental gerontology 2003-04, Vol.38 (4), p.463-470
Main Authors: Schirmer, M., Calamia, K.T., Wenger, M., Klauser, A., Salvarani, C., Moncayo, R.
Format: Article
Language:English
Subjects:
Aged
Alzheimer Disease - diagnostic imaging
Animals
Aortic Aneurysm - diagnostic imaging
Arteriosclerosis - diagnostic imaging
Autoimmune disease
Autoimmune Diseases - diagnostic imaging
Diagnosis
Fever of Unknown Origin - diagnostic imaging
Fluorodeoxyglucose F18
Geriatrics - methods
Humans
Imaging technique
Inflammation
Models, Animal
Radionuclide
Radiopharmaceuticals
Tomography, Emission-Computed
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Description
Summary:18F-Fluorodeoxyglucose-positron emission tomography ( 18F-FDG-PET) is a new functional imaging technique available for clinical and experimental use. 18F-FDG-PET studies can be used for screening, localization and follow-up of hypermetabolic processes including malignancies, infections and autoimmune processes. For several years it has been applied in oncological, cardiological and neurological patients, but nowadays an increasing number of studies favours its use in patients with autoimmune diseases including large vessel arteritis. From the experimental view, this technique has even become more important since the introduction of a small PET scanner for the use in animal models. This review focuses on technical aspects, clinical experiences and experimental and future perspectives of 18F-FDG-PET, with a special emphasis on large vessel vasculitis and other autoimmune diseases.
ISSN:0531-5565
1873-6815
DOI:10.1016/S0531-5565(02)00267-X