SECONDARY METABOLITES BY CHEMICAL SCREENING. 20: DECARESTRICTINES, A NEW FAMILY OF INHIBITORS OF CHOLESTEROL BIOSYNTHESIS FROM PENICILLIUM: III. DECARESTRICTINES E TO M

A detailed examination of the culture broth of Penicillium simplicissimum (strain FH-A 6090) resulted in the detection of minor components of the decarestrictine family. This paper describes the purification, the structures as well as the antihyperlipidemic activities of these novel secondary metabo...

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Bibliographic Details
Published in:Journal of antibiotics 1992/07/25, Vol.45(7), pp.1176-1181
Main Authors: GRABLEY, SUSANNE, HAMMANN, PETER, HÜTTER, KLAUS, KIRSCH, REINHARD, KLUGE, HEINZ, THIERICKE, RALF, MAYER, MARION, ZEECK, AXEL
Format: Article
Language:English
Subjects:
Acetates - analysis
Acetic Acid
Anticholesteremic Agents - analysis
Anticholesteremic Agents - pharmacology
Lactones - analysis
Lactones - pharmacology
Magnetic Resonance Spectroscopy
Penicillium
Penicillium - chemistry
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Summary:A detailed examination of the culture broth of Penicillium simplicissimum (strain FH-A 6090) resulted in the detection of minor components of the decarestrictine family. This paper describes the purification, the structures as well as the antihyperlipidemic activities of these novel secondary metabolites.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.45.1176