Loading…

Severe chronic sensory-motor polyneuropathy: coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature

We present the case of a 58‐year‐old man, who has suffered from type 1 diabetes mellitus since he was young. He had monoclonal IgM kappa gammopathy of undetermined significance and high anti‐MAG antibody titer. He developed a polyneuropathic picture with the clinical and laboratory features of chron...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of the peripheral nervous system 2003-03, Vol.8 (1), p.23-28
Main Authors:	Micco, Andrea, Nobile-Orazio, Eduardo, Baron, Pierluigi, Conti, Giancarlo, Napoli, Laura, Serafini, Massimo, Scarlato, Guglielmo, Scarpini, Elio
Format:	Article
Language:	English
Subjects:	Chronic Disease chronic inflammatory demyelinating polyneuropathy diabetes mellitus Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - pathology Diabetic Neuropathies - etiology Diabetic Neuropathies - pathology Humans Male Middle Aged monoclonal gammopathy of undetermined significance paraproteinemic neuropathy Polyneuropathies - etiology Polyneuropathies - pathology
Citations:	Items that this one cites
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by
cites	cdi_FETCH-LOGICAL-c3495-c94e4a9e4c29cb9159171e3390fe3178ef352380b3403f96c29494bf3722fa5b3
container_end_page	28
container_issue	1
container_start_page	23
container_title	Journal of the peripheral nervous system
container_volume	8
creator	Micco, Andrea Nobile-Orazio, Eduardo Baron, Pierluigi Conti, Giancarlo Napoli, Laura Serafini, Massimo Scarlato, Guglielmo Scarpini, Elio
description	We present the case of a 58‐year‐old man, who has suffered from type 1 diabetes mellitus since he was young. He had monoclonal IgM kappa gammopathy of undetermined significance and high anti‐MAG antibody titer. He developed a polyneuropathic picture with the clinical and laboratory features of chronic inflammatory demyelinating polyneuropathy within the span of approximately 2 years. He benefited from IV administration of high doses of immunoglobulins. Investigation of all parameters, but particularly of the clinical phenotype, can lead to a better definition of the polyneuropathic picture, especially for therapeutic and prognostic purposes.
doi_str_mv	10.1046/j.1529-8027.2003.03005.x
format	article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73173357</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73173357</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3495-c94e4a9e4c29cb9159171e3390fe3178ef352380b3403f96c29494bf3722fa5b3</originalsourceid><addsrcrecordid>eNqNkcFu1DAQhiMEoqXwCmhO3BLsOF7HHJCqFWyLShEqqEfL8U5YL9k4tZ128yx9WRx2Va6c_EvzzWdp_iwDSgpKqsX7bUF5KfOalKIoCWEFYYTwYv8sO30aPE-Z1DyXVS1PslchbAmhQlL5Mjuh5ULUnNPT7PEG79EjmI13vTUQsA_OT_nORedhcN3U4-jdoONm-gDG4d6GiL1BcC0wGHuPnY64BozWde6XxQC2Bw1xGhAorK1u0shAMljsYwHnYHRA8Dg4H0H36xTvLT7MwrhB6GxEr-Po8XX2otVdwDfH9yz7-fnTj-VFfvVtdbk8v8oNqyTPjayw0hIrU0rTSMolFRQZk6RFRkWNLeMlq0nDKsJauUhYJaumZaIsW80bdpa9O3gH7-5GDFHtbDDYdbpHNwYlkoUxLhJYH0DjXQgeWzV4u9N-UpSouRi1VfP91Xx_NRej_haj9mn17fGPsdnh-t_isYkEfDwAD7bD6b_F6sv1DZ9jEuQHwVzQ_kmg_W-1EExwdXu9UsvbWpKvF9_Viv0BOBKttQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73173357</pqid></control><display><type>article</type><title>Severe chronic sensory-motor polyneuropathy: coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Micco, Andrea ; Nobile-Orazio, Eduardo ; Baron, Pierluigi ; Conti, Giancarlo ; Napoli, Laura ; Serafini, Massimo ; Scarlato, Guglielmo ; Scarpini, Elio</creator><creatorcontrib>Micco, Andrea ; Nobile-Orazio, Eduardo ; Baron, Pierluigi ; Conti, Giancarlo ; Napoli, Laura ; Serafini, Massimo ; Scarlato, Guglielmo ; Scarpini, Elio</creatorcontrib><description>We present the case of a 58‐year‐old man, who has suffered from type 1 diabetes mellitus since he was young. He had monoclonal IgM kappa gammopathy of undetermined significance and high anti‐MAG antibody titer. He developed a polyneuropathic picture with the clinical and laboratory features of chronic inflammatory demyelinating polyneuropathy within the span of approximately 2 years. He benefited from IV administration of high doses of immunoglobulins. Investigation of all parameters, but particularly of the clinical phenotype, can lead to a better definition of the polyneuropathic picture, especially for therapeutic and prognostic purposes.</description><identifier>ISSN: 1085-9489</identifier><identifier>EISSN: 1529-8027</identifier><identifier>DOI: 10.1046/j.1529-8027.2003.03005.x</identifier><identifier>PMID: 12678551</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Inc</publisher><subject>Chronic Disease ; chronic inflammatory demyelinating polyneuropathy ; diabetes mellitus ; Diabetes Mellitus, Type 1 - complications ; Diabetes Mellitus, Type 1 - pathology ; Diabetic Neuropathies - etiology ; Diabetic Neuropathies - pathology ; Humans ; Male ; Middle Aged ; monoclonal gammopathy of undetermined significance ; paraproteinemic neuropathy ; Polyneuropathies - etiology ; Polyneuropathies - pathology</subject><ispartof>Journal of the peripheral nervous system, 2003-03, Vol.8 (1), p.23-28</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3495-c94e4a9e4c29cb9159171e3390fe3178ef352380b3403f96c29494bf3722fa5b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12678551$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Micco, Andrea</creatorcontrib><creatorcontrib>Nobile-Orazio, Eduardo</creatorcontrib><creatorcontrib>Baron, Pierluigi</creatorcontrib><creatorcontrib>Conti, Giancarlo</creatorcontrib><creatorcontrib>Napoli, Laura</creatorcontrib><creatorcontrib>Serafini, Massimo</creatorcontrib><creatorcontrib>Scarlato, Guglielmo</creatorcontrib><creatorcontrib>Scarpini, Elio</creatorcontrib><title>Severe chronic sensory-motor polyneuropathy: coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature</title><title>Journal of the peripheral nervous system</title><addtitle>J Peripher Nerv Syst</addtitle><description>We present the case of a 58‐year‐old man, who has suffered from type 1 diabetes mellitus since he was young. He had monoclonal IgM kappa gammopathy of undetermined significance and high anti‐MAG antibody titer. He developed a polyneuropathic picture with the clinical and laboratory features of chronic inflammatory demyelinating polyneuropathy within the span of approximately 2 years. He benefited from IV administration of high doses of immunoglobulins. Investigation of all parameters, but particularly of the clinical phenotype, can lead to a better definition of the polyneuropathic picture, especially for therapeutic and prognostic purposes.</description><subject>Chronic Disease</subject><subject>chronic inflammatory demyelinating polyneuropathy</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus, Type 1 - complications</subject><subject>Diabetes Mellitus, Type 1 - pathology</subject><subject>Diabetic Neuropathies - etiology</subject><subject>Diabetic Neuropathies - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>monoclonal gammopathy of undetermined significance</subject><subject>paraproteinemic neuropathy</subject><subject>Polyneuropathies - etiology</subject><subject>Polyneuropathies - pathology</subject><issn>1085-9489</issn><issn>1529-8027</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqNkcFu1DAQhiMEoqXwCmhO3BLsOF7HHJCqFWyLShEqqEfL8U5YL9k4tZ128yx9WRx2Va6c_EvzzWdp_iwDSgpKqsX7bUF5KfOalKIoCWEFYYTwYv8sO30aPE-Z1DyXVS1PslchbAmhQlL5Mjuh5ULUnNPT7PEG79EjmI13vTUQsA_OT_nORedhcN3U4-jdoONm-gDG4d6GiL1BcC0wGHuPnY64BozWde6XxQC2Bw1xGhAorK1u0shAMljsYwHnYHRA8Dg4H0H36xTvLT7MwrhB6GxEr-Po8XX2otVdwDfH9yz7-fnTj-VFfvVtdbk8v8oNqyTPjayw0hIrU0rTSMolFRQZk6RFRkWNLeMlq0nDKsJauUhYJaumZaIsW80bdpa9O3gH7-5GDFHtbDDYdbpHNwYlkoUxLhJYH0DjXQgeWzV4u9N-UpSouRi1VfP91Xx_NRej_haj9mn17fGPsdnh-t_isYkEfDwAD7bD6b_F6sv1DZ9jEuQHwVzQ_kmg_W-1EExwdXu9UsvbWpKvF9_Viv0BOBKttQ</recordid><startdate>200303</startdate><enddate>200303</enddate><creator>Micco, Andrea</creator><creator>Nobile-Orazio, Eduardo</creator><creator>Baron, Pierluigi</creator><creator>Conti, Giancarlo</creator><creator>Napoli, Laura</creator><creator>Serafini, Massimo</creator><creator>Scarlato, Guglielmo</creator><creator>Scarpini, Elio</creator><general>Blackwell Science Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200303</creationdate><title>Severe chronic sensory-motor polyneuropathy: coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature</title><author>Micco, Andrea ; Nobile-Orazio, Eduardo ; Baron, Pierluigi ; Conti, Giancarlo ; Napoli, Laura ; Serafini, Massimo ; Scarlato, Guglielmo ; Scarpini, Elio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3495-c94e4a9e4c29cb9159171e3390fe3178ef352380b3403f96c29494bf3722fa5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Chronic Disease</topic><topic>chronic inflammatory demyelinating polyneuropathy</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus, Type 1 - complications</topic><topic>Diabetes Mellitus, Type 1 - pathology</topic><topic>Diabetic Neuropathies - etiology</topic><topic>Diabetic Neuropathies - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>monoclonal gammopathy of undetermined significance</topic><topic>paraproteinemic neuropathy</topic><topic>Polyneuropathies - etiology</topic><topic>Polyneuropathies - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Micco, Andrea</creatorcontrib><creatorcontrib>Nobile-Orazio, Eduardo</creatorcontrib><creatorcontrib>Baron, Pierluigi</creatorcontrib><creatorcontrib>Conti, Giancarlo</creatorcontrib><creatorcontrib>Napoli, Laura</creatorcontrib><creatorcontrib>Serafini, Massimo</creatorcontrib><creatorcontrib>Scarlato, Guglielmo</creatorcontrib><creatorcontrib>Scarpini, Elio</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the peripheral nervous system</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Micco, Andrea</au><au>Nobile-Orazio, Eduardo</au><au>Baron, Pierluigi</au><au>Conti, Giancarlo</au><au>Napoli, Laura</au><au>Serafini, Massimo</au><au>Scarlato, Guglielmo</au><au>Scarpini, Elio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Severe chronic sensory-motor polyneuropathy: coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature</atitle><jtitle>Journal of the peripheral nervous system</jtitle><addtitle>J Peripher Nerv Syst</addtitle><date>2003-03</date><risdate>2003</risdate><volume>8</volume><issue>1</issue><spage>23</spage><epage>28</epage><pages>23-28</pages><issn>1085-9489</issn><eissn>1529-8027</eissn><abstract>We present the case of a 58‐year‐old man, who has suffered from type 1 diabetes mellitus since he was young. He had monoclonal IgM kappa gammopathy of undetermined significance and high anti‐MAG antibody titer. He developed a polyneuropathic picture with the clinical and laboratory features of chronic inflammatory demyelinating polyneuropathy within the span of approximately 2 years. He benefited from IV administration of high doses of immunoglobulins. Investigation of all parameters, but particularly of the clinical phenotype, can lead to a better definition of the polyneuropathic picture, especially for therapeutic and prognostic purposes.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Inc</pub><pmid>12678551</pmid><doi>10.1046/j.1529-8027.2003.03005.x</doi><tpages>6</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 1085-9489
ispartof	Journal of the peripheral nervous system, 2003-03, Vol.8 (1), p.23-28
issn	1085-9489 1529-8027
language	eng
recordid	cdi_proquest_miscellaneous_73173357
source	Wiley-Blackwell Read & Publish Collection
subjects	Chronic Disease chronic inflammatory demyelinating polyneuropathy diabetes mellitus Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - pathology Diabetic Neuropathies - etiology Diabetic Neuropathies - pathology Humans Male Middle Aged monoclonal gammopathy of undetermined significance paraproteinemic neuropathy Polyneuropathies - etiology Polyneuropathies - pathology
title	Severe chronic sensory-motor polyneuropathy: coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T22%3A35%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Severe%20chronic%20sensory-motor%20polyneuropathy:%20coexistence%20of%203%20unrelated%20etiologies%20in%20a%20type%201%20diabetic%20patient.%20A%20case%20report%20and%20review%20of%20the%20literature&rft.jtitle=Journal%20of%20the%20peripheral%20nervous%20system&rft.au=Micco,%20Andrea&rft.date=2003-03&rft.volume=8&rft.issue=1&rft.spage=23&rft.epage=28&rft.pages=23-28&rft.issn=1085-9489&rft.eissn=1529-8027&rft_id=info:doi/10.1046/j.1529-8027.2003.03005.x&rft_dat=%3Cproquest_cross%3E73173357%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3495-c94e4a9e4c29cb9159171e3390fe3178ef352380b3403f96c29494bf3722fa5b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=73173357&rft_id=info:pmid/12678551&rfr_iscdi=true