ABH-related antigens in human male genital tract. A histochemical examination

The localization of ABH related antigens in human male reproductive tract was examined using monoclonal antibodies and an avidin biotin complex method. No positive reaction with blood group antibodies on spermatozoa was observed in testis and ductus epididymidis apart from erythrocytes and endotheli...

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Bibliographic Details
Published in:International journal of legal medicine 1992-08, Vol.105 (2), p.75-80
Main Authors: Nishi, K, Fukunaga, T, Yamamoto, Y, Yamada, M, Kane, M, Tanegashima, A, Rand, S, Brinkmann, B
Format: Article
Language:English
Subjects:
ABO Blood-Group System - genetics
ABO Blood-Group System - immunology
Antibodies, Monoclonal
Avidin
Biotin
Evaluation Studies as Topic
Forensic Medicine - methods
Gene Expression
Genitalia, Male - anatomy & histology
Humans
Immunohistochemistry - methods
Isoantigens - analysis
Male
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Summary:The localization of ABH related antigens in human male reproductive tract was examined using monoclonal antibodies and an avidin biotin complex method. No positive reaction with blood group antibodies on spermatozoa was observed in testis and ductus epididymidis apart from erythrocytes and endothelial cells. The expression of ABH and ABH related antigens in ductuli efferents testis, ductus epididymidis, seminal vesicle and prostate was complexly coded by a combination of H, Se, Le and X genes. The results obtained in this study indicate that the ABH antigens detected on spermatozoa of seminal stains are coating antigens and not inherent to the cell membrane, and the ABO, H, Se, Le and X genes are subjected to a tissue-dependent differential expression.
ISSN:0937-9827
1437-1596
DOI:10.1007/BF02340827