Pericardial Involvement in End-Stage Renal Disease

Pericardial involvement in end-stage renal disease (ESRD) is manifested most commonly as acute uremic or dialysis pericarditis and infrequently as chronic constrictive pericarditis. The causes of uremic and dialysis pericarditis remain uncertain. The clinical and laboratory manifestations of acute p...

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Bibliographic Details
Published in:The American journal of the medical sciences 2003-04, Vol.325 (4), p.228-236
Main Authors: Alpert, Martin A., Ravenscraft, Mark D.
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Dialysis pericarditis
End-stage renal disease (ESRD)
Glucocorticoids - therapeutic use
Humans
Kidney Failure, Chronic - physiopathology
Kidney Transplantation
Pericardial effusion
Pericarditis - etiology
Pericarditis - pathology
Pericarditis - physiopathology
Pericarditis - therapy
Pericardium - surgery
Renal Dialysis
Uremia - complications
Uremic pericarditis
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Summary:Pericardial involvement in end-stage renal disease (ESRD) is manifested most commonly as acute uremic or dialysis pericarditis and infrequently as chronic constrictive pericarditis. The causes of uremic and dialysis pericarditis remain uncertain. The clinical and laboratory manifestations of acute pericarditis, pericardial effusion, cardiac tamponade, and constrictive pericarditis in patients with chronic renal failure are similar to those observed in nonuremic patients with similar pericardial involvement, except that chest pain occurs less frequently in those with ESRD. Therapeutic interventions for acute uremic or dialysis pericarditis with or without pericardial effusion include intensive hemodialysis, pericardiocentesis (infrequently used), pericardiostomy with or without instillation of intrapericardial glucocorticoids, pericardial window, and pericardiectomy. Chronic constrictive pericarditis is treated with pericardiectomy.
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-200304000-00009