Transnational stability of gender differences in schizophrenia? An analysis based on the WHO study on determinants of outcome of severe mental disorders

Gender-specific analyses of the multinational WHO-Determinants of Outcome-Study (including 1,292 cases from 10 countries) demonstrate the transnational stability of major findings on gender differences in schizophrenia: Male patients have an earlier mean age at onset in all countries. In female pati...

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Bibliographic Details
Published in:European archives of psychiatry and clinical neuroscience 1992-09, Vol.242 (1), p.6-12
Main Authors: Hambrecht, M, Maurer, K, Häfner, H, Sartorius, N
Format: Article
Language:English
Subjects:
Adult
Age Factors
Colombia - epidemiology
Cross-Cultural Comparison
Europe - epidemiology
Female
Humans
India - epidemiology
Japan - epidemiology
Male
Nigeria - epidemiology
Retrospective Studies
Schizophrenia - diagnosis
Schizophrenia - epidemiology
Schizophrenic Psychology
Sex Factors
Sick Role
United States - epidemiology
World Health Organization
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Summary:Gender-specific analyses of the multinational WHO-Determinants of Outcome-Study (including 1,292 cases from 10 countries) demonstrate the transnational stability of major findings on gender differences in schizophrenia: Male patients have an earlier mean age at onset in all countries. In female patients, the distribution of the age at onset shows a second peak after age 40 years. No gender differences on nuclear symptoms of schizophrenia can be detected, but on uncharacteristic symptoms, particularly some aspects of the illness behaviour, differences appear. This investigation supports the transcultural validity of gender differences found in the German ABC-Schizophrenia-Study and in the Danish-German Psychiatric Case Register studies.
ISSN:0940-1334
1433-8491
DOI:10.1007/BF02190336