Association between short-term simvastatin therapy before coronary artery bypass grafting and postoperative myocardial blood flow as assessed by positron emission tomography

We hypothesized that preoperative simvastatin therapy would be associated with improvements in myocardial perfusion on positron emission tomography scanning above and beyond what may be expected strictly from the placement of bypass conduits.

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Bibliographic Details
Published in:The American journal of cardiology 2003-05, Vol.91 (9), p.1107-1109
Main Authors: Dotani, M.Imran, Morise, Anthony P., Haque, Reyaz, Jain, Abnash C., Gupta, Naresh, Gibson, C.Michael
Format: Article
Language:English
Subjects:
Aged
Cardiovascular disease
Coronary Artery Bypass
Coronary Circulation - drug effects
Coronary Disease - drug therapy
Coronary Disease - physiopathology
Coronary Disease - surgery
Double-Blind Method
Humans
Hypolipidemic Agents - pharmacology
Hypolipidemic Agents - therapeutic use
Middle Aged
Multivariate Analysis
Postoperative Period
Premedication
Prospective Studies
Scientific imaging
Simvastatin - pharmacology
Simvastatin - therapeutic use
Tomography, Emission-Computed
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Description
Summary:We hypothesized that preoperative simvastatin therapy would be associated with improvements in myocardial perfusion on positron emission tomography scanning above and beyond what may be expected strictly from the placement of bypass conduits.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(03)00158-9