Biological screening of Annonaceous Brazilian Medicinal Plants using Artemia salina (Brine Shrimp Test)

Eighteen different extracts from five Annona species collected in Minas Gerais state, Brazil, were submitted to the brine shrimp lethality test in order to detect potential sources of novel cytotoxic, antitumor, pesticidal and anti- Trypanosoma cruzi compounds. All of the Annonaceous species tested...

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Bibliographic Details
Published in:Phytomedicine (Stuttgart) 2003-03, Vol.10 (2), p.209-212
Main Authors: Santos Pimenta, L.P., Pinto, G.B., Takahashi, J.A., e Silva, L.G.F., Boaventura, M.A.D.
Format: Article
Language:English
Subjects:
acetogenins and alkaloids
Alkaloids
Animals
Annona
Annonaceae
Antimitotic agents
Antineoplastic agents
Artemia
Artemia - drug effects
Biological Products - pharmacology
Brazil
brine shrimp larvicidal activity
Composition
Demographic aspects
Larva - drug effects
Medicinal plants
Physiological aspects
Plant Extracts - pharmacology
Plants, Medicinal
Polyketides
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Summary:Eighteen different extracts from five Annona species collected in Minas Gerais state, Brazil, were submitted to the brine shrimp lethality test in order to detect potential sources of novel cytotoxic, antitumor, pesticidal and anti- Trypanosoma cruzi compounds. All of the Annonaceous species tested showed good larvicidal activity as compared to a reference compounds and literature data.
ISSN:0944-7113
1618-095X
DOI:10.1078/094471103321659960