A Methodology for Simulating the Impact of DNA-probe Services on the Outcomes of Pregnancies

For certain single-gene disorders, DNA probes allow individuals to make more informed decisions about family size and the outcomes of pregnancies. They may also have important psychological effects. We present a method of assessing their impact on the outcomes of pregnancy. We conclude that the trad...

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Bibliographic Details
Published in:International journal of technology assessment in health care 1992, Vol.8 (3), p.539-545
Main Authors: Beech, Roger, Rona, Roberto J., Swan, Anthony V., Wilson, Oonagh M., Mandalia, Sundhiya
Format: Article
Language:English
Subjects:
Decision Making
DNA Probes
Female
General Essays
Humans
Outcome Assessment (Health Care)
Pregnancy
Pregnancy Outcome
Prenatal Diagnosis - standards
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Summary:For certain single-gene disorders, DNA probes allow individuals to make more informed decisions about family size and the outcomes of pregnancies. They may also have important psychological effects. We present a method of assessing their impact on the outcomes of pregnancy. We conclude that the traditional approach, which focuses solely on the potential of prenatal diagnostic services to reduce affected births, is limited. It neglects the potential of such services to promote an increase in unaffected births by reducing the number of unnecessary terminations.
ISSN:0266-4623
1471-6348
DOI:10.1017/S0266462300013805