Comparison of daily urine, sweat, and skin swabs among cocaine users

This study (1) compares urine, skin swabs, and PharmChek™ sweat patches for monitoring drug use; (2) measures possible environmental contamination in recent cocaine (COC) users; and (3) evaluates various immunoassays (IA) for screening COC in diverse matrices. Unique aspects include daily urine moni...

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Bibliographic Details
Published in:Forensic science international 2003-04, Vol.133 (1), p.63-78
Main Authors: Kidwell, D.A., Kidwell, J.D., Shinohara, F., Harper, C., Roarty, K., Bernadt, K., McCaulley, R.A., Smith, F.P.
Format: Article
Language:English
Subjects:
Adult
Attorneys
Biological and medical sciences
Cocaine
Cocaine - analysis
Dopamine Uptake Inhibitors - analysis
Drug addictions
Drug dosages
Drug testing
Drug use
Environmental contamination
Federal court decisions
Female
Forensic sciences
Gas Chromatography-Mass Spectrometry
Humans
Immunoassay
Litigation
Male
Medical sciences
Methamphetamine
Middle Aged
Molecular weight
Prosecutions
Skin - chemistry
Substance Abuse Detection - methods
Supreme Court decisions
Sweat
Sweat - chemistry
Testimony
Toxicology
Urine
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Summary:This study (1) compares urine, skin swabs, and PharmChek™ sweat patches for monitoring drug use; (2) measures possible environmental contamination in recent cocaine (COC) users; and (3) evaluates various immunoassays (IA) for screening COC in diverse matrices. Unique aspects include daily urine monitoring of 10 participants for 4 weeks, multiple monitoring methods, analysis for all specimens by IA and gas chromatography (GC)/mass spectrometry (MS), and the potential for continued illicit drug use by participants. Urine served as the “gold standard” specimen for determining drug use. Only cocaine and related substances were detected. Trace amounts of drugs were found on the skin (
ISSN:0379-0738
1872-6283
DOI:10.1016/S0379-0738(03)00051-3