Adenocarcinoid of the appendix: report of two cases

Adenocarcinoid of the appendix is a rare tumor with the histological features of both adenocarcinoma and carcinoid tumor. However, its biological behavior and malignant potential are still unclear. We treated two patients with this unusual tumor; a 60-year-old man and a 79-year-old woman. Both patie...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2003-01, Vol.33 (5), p.375-378
Main Authors: Aizawa, Masaki, Watanabe, Osamu, Naritaka, Yoshihiko, Katsube, Takao, Imamura, Hiroshi, Kinoshita, Jun, Shimakawa, Takeshi, Kobayashi, Satoshi, Asaka, Shinichi, Haga, Shunsuke, Ogawa, Kenji, Aiba, Motohiko, Kajiwara, Tetsuro
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnostic imaging
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Aged
Appendiceal Neoplasms - diagnostic imaging
Appendiceal Neoplasms - pathology
Appendiceal Neoplasms - surgery
Carcinoid Tumor - diagnostic imaging
Carcinoid Tumor - pathology
Carcinoid Tumor - surgery
Female
Humans
Male
Middle Aged
Radiography
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Summary:Adenocarcinoid of the appendix is a rare tumor with the histological features of both adenocarcinoma and carcinoid tumor. However, its biological behavior and malignant potential are still unclear. We treated two patients with this unusual tumor; a 60-year-old man and a 79-year-old woman. Both patients were initially diagnosed with acute appendicitis followed by an appendectomy. At surgery, the appendix was seen to be acutely inflamed without any macroscopic signs of tumor. Postoperative histological analysis revealed an adenocarcinoid tumor in the appendix, which had spread diffusely into its wall without forming a mass. Immunohistochemical staining with p53, MIB-1, bcl-2, and carcinoembryonic antigen suggested that neither of these tumors were particularly aggressive. Adenocarcinoid of the appendix is a rare tumor, which is very difficult to diagnose preoperatively and even macroscopically, making histological examination essential.
ISSN:0941-1291
1436-2813
DOI:10.1007/s005950300085