Effects of Stimulus-Response Compatibility on Neural Selection in Frontal Eye Field

• Published in: Neuron (Cambridge, Mass.) Mass.), 2003-05, Vol.38 (4), p.637-648
• Main Authors: Sato, Takashi R., Schall, Jeffrey D.
• Format: Article
• Language: English
• Subjects: Animals; Attention - physiology; Brain Mapping; Eye movements; Frontal Lobe - cytology; Frontal Lobe - physiology; Macaca radiata; Neurons; Neurons - physiology; Orientation - physiology; Photic Stimulation; Reaction Time - physiology; Response time; Saccades - physiology; Standard deviation; Visual Fields - physiology; Visual Perception - physiology
• ISSN: 0896-6273; 1097-4199
• DOI: 10.1016/S0896-6273(03)00237-X

We investigated the neural basis of visual and saccade selection in the frontal eye field of macaque monkeys using a singleton search task with prosaccade or antisaccade responses. Two types of neurons were distinguished. The first initially selected the singleton even in antisaccade trials, although most subsequently selected the endpoint of the saccade. The time the singleton was located was not affected by stimulus-response compatibility and did not vary with reaction time across trials. The second type of neuron selected only the endpoint of the saccade. The time of endpoint selection by these neurons accounted for most of the effect of stimulus-response compatibility on reaction time. These results indicate that visual selection and saccade selection are different processes.