Common Transfusion-transmitted Infectious Agents among Thalassaemic Children in Bangladesh

Transfusion-dependent children are more prone to acquiring various transfusion-transmitted infections (TTIs), such as hepatitis B (HBV), hepatitis C (HCV), HIV, and others. Since the magnitude of these infections among thalassaemic children in Bangladesh is not well-known, this study was conducted t...

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Bibliographic Details
Published in:Journal of health, population and nutrition population and nutrition, 2003-03, Vol.21 (1), p.67-71
Main Authors: Mollah, Abid Hossain, Nahar, Nazmun, Siddique, Md. A., Anwar, Kazi Selim, Hassan, Tariq, Azam, Md. Golam
Format: Article
Language:English
Subjects:
Adolescent
Antibodies
Bangladesh
Blood
Blood transfusion
Blood transfusions
Care and treatment
Child
Child, Preschool
Children
Children & youth
Diagnosis
Disease transmission
Female
Genetic disorders
Health aspects
Hepatitis
Hepatitis antigens
Hepatitis B
Hepatitis B - blood
Hepatitis B - etiology
Hepatitis B virus
Hepatitis C
Hepatitis C - blood
Hepatitis C - etiology
HIV
HIV Infections - blood
HIV Infections - etiology
Human immunodeficiency virus
Humans
Infant
Infection
Infections
Male
Risk factors
Seroepidemiologic Studies
Serologic Tests
Thalassemia
Thalassemia - blood
Thalassemia - complications
Thalassemia - therapy
Transfusion Reaction
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Summary:Transfusion-dependent children are more prone to acquiring various transfusion-transmitted infections (TTIs), such as hepatitis B (HBV), hepatitis C (HCV), HIV, and others. Since the magnitude of these infections among thalassaemic children in Bangladesh is not well-known, this study was conducted to assess the prevalence of TTIs among them (who received more than three blood transfusions) compared to their age- and sex-matched controls (non-thalassaemics and those who had never had a transfusion). Seromarkers for HBV, HCV, HDV, Treponema pallidum, and HIV were tested, and the results were analyzed using SPSS/Windows 10.5. Of 259 children studied, 152 (58.69%) were thalassaemic (mean age 6.8±3.6 years), and 107 were controls (mean age 6.7±3.53 years). The HBV and HCV-markers were found significantly more often among multi-transfused thalassaemic children than among the controls in terms of HBsAg (13.8% vs 6.5%, p
ISSN:1606-0997
2072-1315