Cardiac troponin I in aortic valve disease

Background: Plasma cardiac troponin I levels may be higher than normal in conditions other than ischemic heart disease. We aimed at measuring troponin I levels in aortic valve patients, in which increased values for left ventricular dimensions and pressure are frequently found. Methods: Plasma level...

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Bibliographic Details
Published in:International journal of cardiology 2003-06, Vol.89 (2), p.281-285
Main Authors: Nunes, José Pedro L., Mota Garcia, J.M., Farinha, Rui M.B., Carlos Silva, João, Magalhães, Domingos, Vidal Pinheiro, Luı́s, Abreu Lima, Cassiano
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Aortic Valve Insufficiency - blood
Aortic Valve Stenosis - blood
Biological and medical sciences
Biomarkers - blood
Cardiology. Vascular system
Endocardial and cardiac valvular diseases
Female
Heart
Heart Ventricles - pathology
Humans
Male
Medical sciences
Middle Aged
Troponin I - blood
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Summary:Background: Plasma cardiac troponin I levels may be higher than normal in conditions other than ischemic heart disease. We aimed at measuring troponin I levels in aortic valve patients, in which increased values for left ventricular dimensions and pressure are frequently found. Methods: Plasma levels of troponin I, creatine kinase (CK) and the MB fraction of the same enzyme were measured in a group of 25 clinically stable aortic valve patients. Echocardiographic study was performed in all patients; hemodynamic and coronary angiographic study was performed in 19 patients. Troponin I was also measured in a control population ( n=305). Results: The mean value for troponin I was found to be higher in aortic valve patients (0.07±0.02 ng/ml), when compared to controls (0.01±0.02 ng/ml; P
ISSN:0167-5273
1874-1754
DOI:10.1016/S0167-5273(02)00502-8