Granular Parakeratosis in Children: Case Report and Review of the Literature

: Granular parakeratosis is a cutaneous eruption with erythematous and/or brownish hyperkeratotic papules and plaques which are exclusively localized to intertriginous areas and show histopathologic features of an unusual form of parakeratosis. The etiology is unknown, but the excessive use of vario...

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Bibliographic Details
Published in:Pediatric dermatology 2003-05, Vol.20 (3), p.215-220
Main Authors: Pimentel, Dalva Regina Neto, Michalany, Nilceo, Morgado de Abreu, Marilda Aparecida Milanêz, Petlik, Beno, Alchorne, Maurício Mota de Avelar
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle
Dermatology
Dyskeratosis
Female
Humans
Immunohistochemistry
Infant
Medical sciences
Parakeratosis - pathology
Remission, Spontaneous
Severity of Illness Index
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Summary:: Granular parakeratosis is a cutaneous eruption with erythematous and/or brownish hyperkeratotic papules and plaques which are exclusively localized to intertriginous areas and show histopathologic features of an unusual form of parakeratosis. The etiology is unknown, but the excessive use of various topical preparations (e.g., ointments and deodorants) has been associated with this disease. It has heretofore been reported only in adults. We report two children, ages 3 and 5 months, with characteristic lesions in the groin associated with topical pomades used to prevent diaper rash. This is the first report associating the clinical presentation and the histopathologic diagnosis of granular parakeratosis in children. The literature on this entity is also reviewed and all case reports are summarized.
ISSN:0736-8046
1525-1470
DOI:10.1046/j.1525-1470.2003.20306.x