Beneficial effects of preoperative intravitreal bevacizumab on trabeculectomy outcomes in neovascular glaucoma

. Purpose:  This study aimed to investigate the effects of preoperative intravitreal bevacizumab (IVB) on outcomes in trabeculectomy for neovascular glaucoma (NVG). Methods:  Charts for 52 NVG eyes of 52 consecutive patients who received primary trabeculectomy with mitomycin C (MMC) were reviewed. P...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2010-02, Vol.88 (1), p.96-102
Main Authors: Saito, Yoshiaki, Higashide, Tomomi, Takeda, Hisashi, Ohkubo, Shinji, Sugiyama, Kazuhisa
Format: Article
Language:English
Subjects:
Aged
Anterior Chamber - blood supply
Antibodies, Monoclonal - administration & dosage
Antibodies, Monoclonal, Humanized
Bevacizumab
Choroid Hemorrhage - etiology
Eye Hemorrhage - etiology
Female
Follow-Up Studies
Glaucoma, Neovascular - physiopathology
Glaucoma, Neovascular - surgery
Humans
Hyphema - prevention & control
Injections, Intraocular
Intraocular Pressure - drug effects
intravitreal injection
Male
Middle Aged
Mitomycin - therapeutic use
neovascular glaucoma
Postoperative Complications - prevention & control
Postoperative Period
Preoperative Care - standards
Recurrence
Retrospective Studies
trabeculectomy
Trabeculectomy - adverse effects
Treatment Outcome
Vitreous Body
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Summary:. Purpose:  This study aimed to investigate the effects of preoperative intravitreal bevacizumab (IVB) on outcomes in trabeculectomy for neovascular glaucoma (NVG). Methods:  Charts for 52 NVG eyes of 52 consecutive patients who received primary trabeculectomy with mitomycin C (MMC) were reviewed. Postoperative follow‐up periods for all patients were ≥ 4 months. Thirty‐two consecutive eyes were treated without IVB (control group) and 20 consecutive eyes received IVB (1.25 mg) 10 ± 11 days before trabeculectomy (IVB group). The main outcome measures were postoperative intraocular pressure (IOP) and incidence of postoperative complications. Surgical success was defined as IOP
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2009.01648.x