Aerobic exercise training programmes for improving physical and psychosocial health in adults with Down syndrome

• Published in: Cochrane database of systematic reviews 2010-05 (5), p.CD005176-CD005176
• Main Authors: Andriolo, Régis B, El Dib, Regina P, Ramos, Luis, Atallah, Alvaro N, da Silva, Edina Mk
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Down Syndrome - physiopathology; Down Syndrome - psychology; Exercise - physiology; Exercise - psychology; Humans; Middle Aged; Physical Fitness - physiology; Physical Fitness - psychology; Program Evaluation; Randomized Controlled Trials as Topic; Young Adult
• ISSN: 1469-493X
• DOI: 10.1002/14651858.CD005176.pub4

Although physical fitness has been suggested to improve physical and psychosocial health for a variety of population profiles, there is a lack of information about the safety and effectiveness of aerobic exercise for adults with Down syndrome. To evaluate the effectiveness and safety of aerobic exercise training programmes for physiological and psychosocial outcomes in adults with Down syndrome. The following electronic databases were searched: The Cochrane Central Register of Controlled Trials (CENTRAL) (2009, Issue 1); MEDLINE (1966 to August 2009); EMBASE (1980 to August 2009); CINAHL (1982 to August 2009); LILACS (1982 to August 2009); PsycINFO (1887 to August 2009); ERIC (1966 to August 2009); Current Controlled Trials (August 2009); and Campbell Collaboration's Social, Psychological, Educational and Criminological Register (C2- SPECTR) (to August 2009). Information about ongoing clinical trials was sought by searching ClinicalTrials.gov (http://clinicaltrials.gov) (accessed August 2009), and the National Research Register (NRR) (2009 Issue 1). Randomised or quasi-randomised controlled trials using supervised aerobic exercise training programmes with behavioral components accepted as co-interventions. Two reviewers selected relevant trials, assessed methodological quality and extracted data. Where appropriate, data were pooled using meta-analysis with a random-effects model. Positive values favour the intervention group, while negative values favour the control group. Three studies included in this systematic review used different kinds of aerobic activity: walking/jogging and rowing training and included participants with a broad age range (17 to 65 years). They were conducted in the USA, Portugal and Israel. In the meta-analyses, only maximal treadmill grade was improved after aerobic exercise training programmes (4.26 grades (%) [95% CI 2.06, 6.45]). Other variables relative to work performance that could not be combined in a meta-analysis were also improved in the intervention group (maximal test time P=0.0003), total turns of fan wheel (P=0.02), resistance of ergometer (p=0.003), power knee extension and flexion (p