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Non-invasive optical mapping of the piglet brain in real time

We have performed non-invasive, real-time optical mapping of the piglet brain during a subcortical injection of autologous blood. The time resolution of the optical maps is 192 ms, thus allowing us to generate a real-time video of the growing subcortical hematoma. The increased absorption at the sit...

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Bibliographic Details
Published in:Optics express 1999-04, Vol.4 (8), p.308-314
Main Authors: Fantini, S, Franceschini, M, Gratton, E, Hueber, D, Rosenfeld, W, Maulik, D, Stubblefield, P, Stankovic, M
Format: Article
Language:English
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Summary:We have performed non-invasive, real-time optical mapping of the piglet brain during a subcortical injection of autologous blood. The time resolution of the optical maps is 192 ms, thus allowing us to generate a real-time video of the growing subcortical hematoma. The increased absorption at the site of blood injection is accompanied by a decreased absorption at the contralateral brain side. This contralateral decrease in the optical absorption and the corresponding time traces of the cerebral hemoglobin parameters are consistent with a reduced cerebral blood flow caused by the increased intracranial pressure.
ISSN:1094-4087
1094-4087
DOI:10.1364/OE.4.000308