Serum glycated albumin, but not glycated haemoglobin, is low in relation to glycemia in hyperuricemic men

• Published in: Acta diabetologica 2010-06, Vol.47 (2), p.173-177
• Main Authors: Koga, Masafumi, Murai, Jun, Saito, Hiroshi, Mukai, Mikio, Kasayama, Soji
• Format: Article
• Language: English
• Subjects: Acids; Blood Glucose - metabolism; Blood Pressure; Body Mass Index; C-Reactive Protein - metabolism; Diabetes; Diagnostic tests; Glucose Tolerance Test; Glycated Hemoglobin A - metabolism; Humans; Hyperuricemia - blood; Hyperuricemia - epidemiology; Hyperuricemia - physiopathology; Inflammatory diseases; Internal Medicine; Male; Medicine; Medicine & Public Health; Mens health; Metabolic Diseases; Obesity - complications; Obesity - epidemiology; Original Article; Patient Selection; Proteins; Reference Values; Regression Analysis; Serum Albumin - metabolism; Uric Acid - blood
• ISSN: 0940-5429; 1432-5233
• DOI: 10.1007/s00592-009-0168-6

Measurements of glycated albumin (GA) as well as glycated haemoglobin (HbA 1C ) have been applied in order to monitor chronic glycemic control in diabetic patients. Since the levels of both glycated proteins are influenced by various factors other than glycemia, cautions are necessary to evaluate such measures in some specific conditions. In this study, we examined the effects of serum uric acid (UA) levels on these glycemic markers. One hundred and ninety-three men with normal glucose tolerance were enrolled in this study. Association of serum UA with BMI, plasma glucose (PG), high sensitivity CRP (hs-CRP), serum GA and HbA 1C was analysed. Serum UA showed a significant positive correlation with BMI ( R  = 0.329, P